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N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide

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N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide Basic information

Product Name:
N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide
Synonyms:
  • N,N'-BIS(1,3-DIHYDROXYPROPAN-2-YL)-5-(2-HYDROXYPROPANOYLAMINO)-2,4,6-TRIIODO-BENZENE-1,3-DICARBOXAMIDE
  • N,N'-Bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-1,3-Benzenedicarboxamide
  • 2-[2-[(7-chloro-4-quinazolinyl)amino]ethoxy]ethanol
  • 1-N,3-N-bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanoylamino)-2,4,6-triiodobenzene-1,3-dicarboxamide
  • N,N'-bis(2-hydroxy-1-methylol-ethyl)-2,4,6-triiodo-5-lactamido-isophthalamide
  • N1,N3-bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanoylamino)-2,4,6-triiodo-benzene-1,3-dicarboxamide
  • 1,3-BenzenedicarboxaMide,N1,N3-bis[2-hydroxy-1-(hydroxyMethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)aMino]-2,4,6-triiodo-
  • (S)-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodoisophthaldiamide
CAS:
62883-00-5
MF:
C17H22I3N3O8
MW:
777.09
EINECS:
262-093-6
Product Categories:
  • Other APIs
Mol File:
62883-00-5.mol
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N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide Chemical Properties

Melting point:
>283oC (dec.)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Water (Slightly)
form 
Solid
pka
pKa 10.70(H2O,t = 25.0) (Uncertain)
color 
White
CAS DataBase Reference
62883-00-5(CAS DataBase Reference)
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N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide Usage And Synthesis

Description

Lopamidol is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. Lopamidol is a Radiographic Contrast Agent, it is a benzenedicarboxamide, an organoiodine compound and a pentol.

Uses

Diagnostic aid (radiopaque medium.

Uses

Lopamidol is a radiopaque (RAY dee oh payk) contrast agent to help diagnose or find problems in the brain, heart, head, blood vessels, and other parts of the body. Iopamidol contains iodine, a substance that absorbs x-rays. Radiopaque contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Definition

ChEBI: Iopamidol is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. It is a benzenedicarboxamide, an organoiodine compound and a pentol.

Indications

Iopamidol is indicated for angiography throughout the cardiovascular system in adults, including cerebral and peripheral arteriography, coronary arteriography and ventriculography, selective visceral arteriography and aortography, peripheral venography (phlebography), and in pediatric patients for angiocardiography; or for intravenous use in adult and pediatric for computed tomographic (CT) imaging of the head and body.

brand name

Isovue (Bracco).

Side effects

Serious Effects: Decreased urination, severe headache, dizziness, convulsion, irregular heart beat, feeling light-headed, fainting, breathing trouble, fever, chills, nausea and vomiting.
Local: Pain, tenderness, redness or skin changes.
Less Common: Joint or muscle pain, back ache, stiff neck, numbness, warmth, or tingly feeling, ringing in the ears, increased sweating, itchy skin, chills, stuffy nose, sneezing, confusion, slurred speech.

N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamideSupplier

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