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ChemicalBook >  Product Catalog >  Organic Chemistry >  Heterocyclic Compounds >  2,6-Bis[(4S)-phenyl-2-oxazolin-2-yl]pyridine

2,6-Bis[(4S)-phenyl-2-oxazolin-2-yl]pyridine

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2,6-Bis[(4S)-phenyl-2-oxazolin-2-yl]pyridine Basic information

Product Name:
2,6-Bis[(4S)-phenyl-2-oxazolin-2-yl]pyridine
Synonyms:
  • (S,S)-2,6-BIS(4-PHENYL-2-OXAZOLIN-2-YL)PYRIDINE
  • (S,S)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-PHENYL-2-OXAZOLINE)
  • (4S)-4-phenyl-2-[6-[(4S)-4-phenyl-4,5-dihydrooxazol-2-yl]-2-pyridinyl]-4,5-dihydrooxazole
  • 2,6-Bis[(4S)-phenyl-2-oxazolin-2-yl]pyridine, 98%, (99% ee)
  • SF150030
  • [S-(R*,R*)]-2,6-BIS(4,5-DIHYDRO-4-PHENYL-2-OXAZOLYL)PYRIDINE
  • 2,6-BIS[(4S)-PHENYL-2-(OXAZOLIN-2-YL)]PYRIDINE
  • (-)-2,6-BIS[(4S)-4-PHENYL-2-OXAZOLIN-2-YL]PYRIDINE
CAS:
174500-20-0
MF:
C23H19N3O2
MW:
369.42
Product Categories:
  • Furans ,Coumarins
  • BOX series
  • Asymmetric Synthesis
  • organic amine
  • Heterocycle-Pyridine series
  • Chiral Nitrogen
  • Synthetic Organic Chemistry
Mol File:
174500-20-0.mol
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2,6-Bis[(4S)-phenyl-2-oxazolin-2-yl]pyridine Chemical Properties

Melting point:
171-175 °C(lit.)
alpha 
-224 º (c=1, chloroform)
Boiling point:
600.4±55.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
crystal
pka
3.07±0.70(Predicted)
color 
white
optical activity
[α]20/D 224°, c = 1 in chloroform
Water Solubility 
Insoluble
CAS DataBase Reference
174500-20-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39-37/39
WGK Germany 
3
HS Code 
29349990

MSDS

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2,6-Bis[(4S)-phenyl-2-oxazolin-2-yl]pyridine Usage And Synthesis

Chemical Properties

White solid

Reactions

1. Ligand for Copper catalyzed syn-selective Mukaiyama aldol reaction.
2. Ligand for Tin catalyzed anti-selective aldol reaction.
3. Ligand for Ytterbuim catalyzed desymmetrization of meso epoxides.
4. Ligand for Copper catalyzed enantioselective addition of terminal alkynes to imines.
5. Ligand for Scandium catalyzed enantioselective syn-selective ene reactions.
6. Ligand for Copper catalysed asymmetric alkynylation of cyclic azomethine Imines.
7. Ligand for Europium catalyzed asymmetric alpha amination.
8. Ligand for Indium catalyzed enantioselective construction of spiro-fused 2-oxindole/α-methylene-γ-butyrolactones.
9. Ligand for Copper catalyzed asymmetric azide-alkyne cycloaddition to quaternary oxindoles.
10. Ligand for Iron catalyzed enantioselective nitrene transfer to sulfides.
11. Ligand for Copper catalyzed enantioselective intramolecular propargylic amination.
12. Ligand for Copper catalyzed asymmetric hydroxylation.
13. Ligand for Scandium catalyzed dearomatization of 2-naphthols by electrophilic amination.
14. Ligand for Copper catalyzed asymmetric alkynylation of oxocarbenium ions to set diaryl tetrasubstituted stereoceters.


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