Hexyl nicotinate Chemical Properties

Boiling point:

140°C

Density 

1,02 g/cm³

refractive index 

1.4880 to 1.4920

storage temp. 

Inert atmosphere,Room Temperature

form 

clear liquid

pka

3.21±0.10(Predicted)

color 

Colorless to Almost colorless

Water Solubility 

0.17g/L(32 ºC)

LogP

3.510

CAS DataBase Reference

23597-82-2(CAS DataBase Reference)

NIST Chemistry Reference

3-Pyridinecarboxylic acid, hexyl ester(23597-82-2)

EPA Substance Registry System

Hexyl nicotinoate (23597-82-2)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HS Code 

29333990

Hexyl nicotinate Usage And Synthesis

Description

Hexyl Nicotinate is an active substance from the group of rubefacients that stimulates blood circulation. It is used for topical treatment of muscle, joint and ligament pain. Hexyl Nicotinate can be used in creams, baths and emulsions, in veterinary as well as in human medicines.

Uses

hexyl nicotinate penetrates rapidly and dilates blood vessels, thereby temporarily activating blood circulation. This increased blood flow results in an enhanced supply of oxygen, nutrients, and moisture to the skin cells, along with a faster elimination of wastes by means of the metabolic process.

Uses

Hexyl Nicotinoate is a nicotinic acid ester prodrug.

Application

Hexyl Nicotinate is used as a cosmetic ingredient in several applications such as Sun tanning lotion, creams, slimming gels, and creams. It is preferred over Niacin due to its better penetrating power.
1.Used in hair loss creams and lotions as vasodilator.
2.Ingradient of Transvasin heat rub cream. (Thornton & Ross)
3.Used in almost all slimming and tanning cosmetic formulations.

benefits

1. Preferred over Niacin due to its better penetrating power.
2. Hexyl Nicotinate demonstrates better rubefacient properties which can produce pronounced thermo-slimming compositions.
3. Hexyl Nicotinate enhances blood circulation in the skin and enhances the skin's metabolism.

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