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beta-nadph tetra(cyclohexylammonium) salt

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beta-nadph tetra(cyclohexylammonium) salt Basic information

Product Name:
beta-nadph tetra(cyclohexylammonium) salt
Synonyms:
  • Codehydrase II, reduced, compd. with cyclohexanamine (1:4)
  • β- NADPH Tetra(Cyclohexammoinum) Salt, Grade I
  • Triphosphopyridine nucleotide, reduced form
  • NADPH'Cy4N-salt
  • NADPH (tetracyclohexanamine)
  • NADPH TETRA(CYCLOHEXYLAMMONIUM) SALT
  • TRIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM TETRA(CYCLOHEXYLAMMONIUM) SALT
  • TPNH TETRA(CYCLOHEXYLAMMONIUM) SALT
CAS:
100929-71-3
MF:
C27H43N8O17P3
MW:
844.6
Mol File:
100929-71-3.mol
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beta-nadph tetra(cyclohexylammonium) salt Chemical Properties

Melting point:
>137°C (dec.)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Water (Slightly)
form 
Solid
color 
Pale Yellow
Stability:
Hygroscopic
InChIKey
ADEFSDINNZTYFL-MYYNGNHWNA-N
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Safety Information

WGK Germany 
3

MSDS

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beta-nadph tetra(cyclohexylammonium) salt Usage And Synthesis

Description

β-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium) salt, is a pivotal cofactor in cellular metabolism, notably used in studying redox reactions where it functions as an electron carrier. In research, it is critical to probe the enzymatic mechanisms and kinetics of NADPH-dependent enzymes, essential for biosynthetic pathways, oxidative stress responses, and immune system functions. As a reduced form of NADP+, it serves as a substrate in assays to quantify the activity of dehydrogenases and reductases, providing insights into regulating metabolic processes. The tetra(cyclohexylammonium) salt form enhances solubility, facilitating its use in various in vitro experiments. Additionally, this compound is integral in photosynthetic research, particularly in studies focused on light-independent reactions where NADPH is consumed to reduce carbon dioxide to glucose.

Uses

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Uses

NADPH (tetracyclohexanamine) is a salt form of NADPH. NADPH is one of the biologically active forms of nicotinic acid. It serves as a coenzyme of hydrogenases and dehydrogenases. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions.

Biochem/physiol Actions

Electron donor; cofactor for nitric oxide synthetase

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