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H-TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2

Basic information Safety Supplier Related

H-TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2 Basic information

Product Name:
H-TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2
Synonyms:
  • NPY (1-24) AMIDE (HUMAN, RAT)
  • NPY (1-24) (HUMAN)
  • NEUROPEPTIDE Y FRAGMENT 1-24 AMIDE HUMAN
  • NEUROPEPTIDE Y (1-24) AMIDE, HUMAN
  • NEUROPEPTIDE Y (1-24) AMIDE (HUMAN, RAT)
  • NEUROPEPTIDE Y (1-24) (HUMAN)
  • YPSKPDNPGEDAPAEDMARYYSAL-NH2
  • TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2
CAS:
131448-51-6
MF:
C116H170N30O40S
MW:
2656.83
Product Categories:
  • peptide
Mol File:
131448-51-6.mol
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H-TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2 Chemical Properties

storage temp. 
−20°C
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Safety Information

WGK Germany 
3

MSDS

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H-TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2 Usage And Synthesis

Uses

Neuropeptide Y (1-24) (human) is a neuropeptide with potencies in inhibiting the electricity stimulated twitch response of rat vas deferens. Neuropeptide Y (1-24) (human) stimulates N-methyl-D-aspartate (NMDA)-induced neuronal activation in the rat CA3 region of the dorsal hippocampus in vivo[1][2].

References

[1] Monnet FP, et al. Neuropeptide Y potentiates selectively the N-methyl-D-aspartate response in the rat CA3 dorsal hippocampus. I. Involvement of an atypical neuropeptide Y receptor. J Pharmacol Exp Ther. 1992 Dec;263(3):1212-8. PMID:1469629
[2] Martel JC, et al Comparative structural requirements of brain neuropeptide Y binding sites and vas deferens neuropeptide Y receptors. Mol Pharmacol. 1990 Oct;38(4):494-502. PMID:2172766

H-TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2Supplier

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