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4-Pyridinealdoxime

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4-Pyridinealdoxime Basic information

Product Name:
4-Pyridinealdoxime
Synonyms:
  • Pyridine, 4-formyl-, oxime
  • ISONICOTINALDEHYDE OXIME
  • ISONICOTINALDOXIME
  • 4-PYRIDINECARBOXALDOXIME
  • 4-PYRIDINECARBALDEHYDE OXIME
  • 4-PYRIDINEALDOXIME
  • PYRIDINE-4-CARBALDOXIME
  • PYRIDINE-4-ALDOXIME
CAS:
696-54-8
MF:
C6H6N2O
MW:
122.12
EINECS:
211-796-6
Product Categories:
  • Pyridines, Pyrimidines, Purines and Pteredines
  • C6
  • Heterocyclic Building Blocks
  • Pyridines
  • Aromatics
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • Building Blocks
  • Chemical Synthesis
  • Heterocyclic Building Blocks
Mol File:
696-54-8.mol
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4-Pyridinealdoxime Chemical Properties

Melting point:
131-133 °C
Boiling point:
227.52°C (rough estimate)
Density 
1.2236 (rough estimate)
vapor pressure 
<0.01 hPa (50 °C)
refractive index 
1.5350 (estimate)
Flash point:
110 °C
storage temp. 
Store below +30°C.
solubility 
10g/l
pka
pK1:4.73(+1);pK2:10.03(0) (25°C)
form 
Solid
color 
White to Off-White
PH
6.3 (10g/l, H2O, 20℃)
Water Solubility 
10 g/L (20 ºC)
BRN 
2079
CAS DataBase Reference
696-54-8(CAS DataBase Reference)
NIST Chemistry Reference
4-Pyridinecarboxaldehyde, oxime(696-54-8)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/22-36/37/38-20/21/22
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
NR9410000
HS Code 
29333999
Toxicity
LD50 orally in Rabbit: 655 mg/kg

MSDS

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4-Pyridinealdoxime Usage And Synthesis

Chemical Properties

white very fine crystalline powder

Uses

It is employed as an intermediate for bis(hydroxyiminomethylpyridinium)butenes and as reactivators of chlorpyrifos-inhibited acetylcholinesterase. It is also used in the chromatographic separation and NMR characterization of the isomers of 1,1?-Methylenebis{4-[(hydroxyimino)methyl]pyridinium) dichloride.

Uses

An intermediate for bis(hydroxyiminomethylpyridinium)butenes as reactivators of chlorpyrifos-inhibited acetylcholinesterase.

Purification Methods

Crystallise the oxime from water. [Beilstein E-isomer 21 III/IV 3533, 21/7 V 355.]

4-Pyridinealdoxime Preparation Products And Raw materials

Raw materials

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