Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Organic Chemistry >  Amides >  Naphthenic amines derivatives >  4-Bromo-2-(trifluoromethoxy)aniline

4-Bromo-2-(trifluoromethoxy)aniline

Basic information Safety Supplier Related

4-Bromo-2-(trifluoromethoxy)aniline Basic information

Product Name:
4-Bromo-2-(trifluoromethoxy)aniline
Synonyms:
  • BUTTPARK 50\01-74
  • TIMTEC-BB SBB005835
  • 2-AMINO-5-BROMO TRIFLUOROMETHOXY BENZENE
  • 4-BROMO-2-(TRIFLUOROMETHOXY)ANILINE
  • 4-bromo-2-(trifluoromrthoxy)aniline
  • 4-Bromo-2-(trifluoromethoxy)aniline 98%
  • 4-Bromo-2-(trifluoromethoxy)aniline98%
  • 4-Bromo-2-trifluoromethoxyaniline,97%
CAS:
175278-09-8
MF:
C7H5BrF3NO
MW:
256.02
Product Categories:
  • Fluorine series
  • Nitrogen Compounds
  • Amines
  • Building Blocks
  • Chemical Synthesis
  • Organic Building Blocks
  • Trifluoroanisole series
  • Anilines, Aromatic Amines and Nitro Compounds
  • C7
  • Nitrogen Compounds
Mol File:
175278-09-8.mol
More
Less

4-Bromo-2-(trifluoromethoxy)aniline Chemical Properties

Boiling point:
98-100 °C/15 mmHg (lit.)
Density 
1.691 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.5130(lit.)
Flash point:
>230 °F
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
1.75±0.10(Predicted)
CAS DataBase Reference
175278-09-8(CAS DataBase Reference)
More
Less

Safety Information

Hazard Codes 
T,Xi
Risk Statements 
25-43-52/53-36/37/38
Safety Statements 
36/37-45-37/39-26
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
2
Hazard Note 
Toxic
HazardClass 
IRRITANT
HazardClass 
6.1
PackingGroup 
HS Code 
29222990

MSDS

More
Less

4-Bromo-2-(trifluoromethoxy)aniline Usage And Synthesis

Chemical Properties

clear pale yellow to orange-yellow liquid

Uses

4-Bromo-2-(trifluoromethoxy)aniline is a versatile building block that can be used to create a range of compounds, such as methyl 4- amino-3-(trifluoromethoxy)benzoate, 1-Bromo-3-(trifluoromethoxy)benzene, etc.
To a solution of 4-bromo-2-(trifluoromethoxy)aniline (10 g, 50.21 mmol) in methanol (150 mL) in a pressure tank reactor was added TEA (11.84 g, 117.01 mmol), Pd(dppf)Ci2 CH2Q2 (2.4 g, 2.94 mmol). Then the reactor was charged with CO (g) (20 atm). The resulting reaction was stirred for 1.5 days at 100°C. Then it was diluted with water (200 mL), extracted with ethyl acetate (3 x 100 mL) and the organic layers combined and dried in an oven under reduced pressure. The resulting mixture was concentrated in a vacuo. The residue was purified by silica gel column chromatography with ethyl acetate/petroleum ether (1:50) to afford methyl 4- amino-3-(trifluoromethoxy)benzoate as yellow solid (5 g, 54 %).

4-Bromo-2-(trifluoromethoxy)anilineSupplier

Shanghai Harvest Chemical Industrial Co., Ltd. Gold
Tel
21-31038972 15721252604
Email
ammyzuo@harvest-chem.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Email
market03@meryer.com
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Email
sales@RHFChem.com