5-METHOXY-L-TRYPTOPHAN Chemical Properties

Melting point:

253-256 °C

Boiling point:

478.3±45.0 °C(Predicted)

Density 

1.347±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

form 

solid

pka

2.22±0.10(Predicted)

color 

off-white to light yellow

optical activity

[α]20/D -30 to -28° in water

InChI

1S/C12H14N2O3/c1-17-8-2-3-11-9(5-8)7(6-14-11)4-10(13)12(15)16/h2-3,5-6,10,14H,4,13H2,1H3,(H,15,16)/t10-/m0/s1

InChIKey

KVNPSKDDJARYKK-JTQLQIEISA-N

SMILES

[N+H3][C@@H](Cc1c2c([nH]c1)ccc(c2)OC)C(=O)[O-]

Safety Information

WGK Germany 

WGK 1

HS Code 

2933998090

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 3 Oral

5-METHOXY-L-TRYPTOPHAN Usage And Synthesis

Uses

(S)-2-Amino-3-(5-methoxy-1H-indol-3-yl)propanoic Acid is a reagent used in the preparation of anti-HIV agent flazine analogues.

Definition

ChEBI: 5-methoxytryptophan is an L-tryptophan derivative that is L-tryptophan with a methoxy substituent at position 5. It has a role as a metabolite. It is functionally related to a L-tryptophan. It is a tautomer of a 5-methoxy-L-tryptophan zwitterion.

References

[1] Patent: WO2016/115188, 2016, A1. Location in patent: Page/Page column 14; 15; 16

5-METHOXY-L-TRYPTOPHAN(25197-96-0)Related Product Information

• 6-CHLORO-L-TRYPTOPHAN
• (S)-2-AMINO-3-(4-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID
• (S)-2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
• 7-CHLORO-L-TRYPTOPHAN
• (S)-2-AMINO-3-(5-CHLORO-1H-INDOL-3-YL)-PROPIONIC ACID
• H-TRP-GLY-OH
• (2S)-2-amino-3-(5-bromo-1H-indol-3-yl)propanoic acid
• 6-broMo-L-tryptophan
• H-TRP(BOC)-OH
• (S)-2-AMINO-3-(4-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
• (S)-2-AMINO-3-(6-FLUORO-1H-INDOL-3-YL)-PROPIONIC ACID
• 7-FLUORO-L-TRYPTOPHAN
• H-TRP-GLY-GLY-OH
• (S)-2-AMINO-3-(7-METHYL-1H-INDOL-3-YL)-PROPIONIC ACID
• 7-Methoxy-L-tryptophan
• 5-METHOXY-DL-TRYPTOPHAN,5-Methoxy-DL-tryptophan, (SR)-2-Amino-3-(5-methoxyindolyl)propionic acid, 98%
• 5-Benzyloxytryptophan
• BOC-5-METHOXY-L-TRYPTOPHAN,N-BOC-5-METHOXY-L-TRYPTOPHAN