4-Bromobenzenesulfonyl chloride Chemical Properties

Melting point:

73-75 °C (lit.)

Boiling point:

153 °C/15 mmHg (lit.)

Density 

1.7910 (estimate)

Flash point:

152-154°C/26mm

storage temp. 

Refrigerator, Under Inert Atmosphere

solubility 

soluble in Chloroform, DMSO

form 

Crystals or Crystalline Powder

color 

White to beige

Water Solubility 

decomposes

Sensitive 

Moisture Sensitive

Merck 

14,1407

BRN 

743518

CAS DataBase Reference

98-58-8(CAS DataBase Reference)

EPA Substance Registry System

Benzenesulfonyl chloride, 4-bromo- (98-58-8)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45-27

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29049020

MSDS

• Language:English Provider:4-Bromobenzenesulfonyl chloride
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4-Bromobenzenesulfonyl chloride Usage And Synthesis

Chemical Properties

white to beige crystals or crystalline powder

Uses

4-Bromobenzenesulfonyl chloride is used as activating agent in the synthesis of oligodeoxyribo- and oligoribo- nucleotides in solution. It also used in the synthesis of 4-(N-allylsulfamoyl)phenylboronic acid and in protection of amines as 4-bromobenzenesulfonamides.

Uses

4-Bromobenzenesulfonyl chloride is used for identification of amines, and also in the synthesis and inhibition studies of substituted N-L-histidinylphenylsulfonyl hydrazide.

Uses

Identification of amines.

Synthesis Reference(s)

Synthesis, p. 1203, 1992 DOI: 10.1055/s-1992-26333

Purification Methods

Wash the sulfonyl chloride with cold water, dry and recrystallise it from pet ether, or from ethyl ether cooled in powdered Dry-Ice after the ether solution had been washed with 10% NaOH until colourless, then dry it with anhydrous Na2SO4. Alternatively dissolve it in CHCl3, wash it with H2O, dry (Na2SO4), evaporate and recrystallise it. [Huntress & Carten J Am Chem Soc 62 511 1940.] Test for the SO2Cl group by dissolving it in EtOH and boiling with NH4CNS whereby a yellow amorphous precipitate forms on cooling. [Beilstein 11 IV 162.]

4-Bromobenzenesulfonyl chloride(98-58-8)Related Product Information

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• Benzenesulfonyl chloride
• Choline chloride
• Ammonium chloride
• Benzyl chloride
• 4-Bromotoluene
• Mepiquat chloride
• 4-Nitrobenzenesulfonyl chloride
• Polyvinyl chloride
• 4-Bromophenol
• Sodium chloride
• 4-Bromoaniline
• 4-Chlorobenzenesulfonyl chloride
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• Methylene Chloride
• 3,4-DIBROMOBENZENESULFONYL CHLORIDE