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Daidzin

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Daidzin Basic information

Product Name:
Daidzin
Synonyms:
  • 4h-1-benzopyran-4-one,7-(beta-d-glucopyranosyloxy)-3-(4-hydroxyphenyl)-5-hydro
  • 7-(beta-d-glucopyranosyloxy)-3-(4-hydroxyphenyl)-5-hydroxy-4h-1-benzopyran-4
  • 7-(beta-d-glucopyranosyloxy)-3-(4-hydroxyphenyl)-5-hydroxy-4h-1-benzopyran-4-on
  • 7,4-dihydroxyisoflavone7-glucoside
  • daidzoside
  • GLUCOSYL-7-DAIDZEIN
  • DAIDZEIN-7-GLUCOSIDE
  • DAIDZEIN-7-O-BETA-D-GLUCOPYRANOSIDE
CAS:
552-66-9
MF:
C21H20O9
MW:
416.38
EINECS:
611-245-3
Product Categories:
  • Inhibitors
  • inhibitor
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • pharmacetical
  • The group of Daidzin
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Aromatics
  • Glucuronides
  • Heterocycles
  • standardized herbal extract
Mol File:
552-66-9.mol
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Daidzin Chemical Properties

Melting point:
234-236°C
alpha 
-24 º (C=0.1g/100ml,dimethylsulfoxide)
Boiling point:
727.6±60.0 °C(Predicted)
Density 
1.572±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Slightly, Sonicated), Methanol (Slightly, Heated)
pka
9.65±0.30(Predicted)
form 
Solid
color 
White to Off-White
λmax
297nm(lit.)
BRN 
59741
LogP
0.369 (est)
CAS DataBase Reference
552-66-9(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
DJ3094000
10
HS Code 
29389090
Toxicity
mouse,LD50,intraperitoneal,> 2gm/kg (2000mg/kg),Pharmaceutical Chemistry Journal Vol. 13, Pg. 51, 1979.

MSDS

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Daidzin Usage And Synthesis

Chemical Properties

White Powder

Uses

A derivative of Daidzein. Inhibitor

Uses

A metabolite of isoflavone derivatives. A derivative of Daidzin. Inhibitor.

Definition

ChEBI: Daidzein 7-O-beta-D-glucoside is a glycosyloxyisoflavone that is daidzein attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is used in the treatment of alcohol dependency (antidipsotropic). It has a role as a plant metabolite. It is a hydroxyisoflavone, a monosaccharide derivative and a 7-hydroxyisoflavones 7-O-beta-D-glucoside. It is functionally related to a daidzein.

General Description

Daidzin is a plant isoflavone glycoside and a potent inhibitor of human mitochondrial aldehyde dehydrogenase (ALDH-I).

Biochem/physiol Actions

Daidzin was the most potent isoflavone glycoside tested in modulating differentiation of bone marrow stromal cells toward osteoblasts and away from adipocytes.

target

IL Receptor | ALDH2

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