Isoacteoside Chemical Properties

Melting point:

220～230℃

Boiling point:

942.9±65.0 °C(Predicted)

Density 

1.60±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

DMSO : ≥ 48 mg/mL (76.85 mM)

form 

Powder

pka

9.32±0.10(Predicted)

color 

White to yellow

Safety Information

HS Code 

29389090

Isoacteoside Usage And Synthesis

Description

Isoverbascoside is a phenylethanoid glycoside that has been found in C. trichotomum and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay and inhibits hydrogen peroxide-induced lipid peroxidation in V79-4 cells when used at a concentration of 10 μg/ml. Isoverbascoside (7.5-30 μM) induces apoptosis and production of reactive oxygen species (ROS) in, and reduces viability of, OVCAR-3 cells. It inhibits tumor growth in an OVCAR-3 mouse xenograft model when administered at a dose of 30 mg/kg. Isoverbascoside (2.5 and 5 mg/kg) decreases brain amyloid deposition and increases exploratory behavior in rats when infused into the cerebral ventricles with amyloid-β (1-42) (Aβ42; ). It also decreases xylene-induced ear edema in mice and increases survival in a mouse model of LPS-induced endotoxic shock.

Uses

Isoacteoside is a possible food antioxidant.

Definition

ChEBI: Isoacteoside is a hydroxycinnamic acid.

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