(R)-3-Isopropyl-2,5-piperazinedione Chemical Properties

Melting point:

258-262 °C(lit.)

alpha 

-31.5 º (c=1, water)

Boiling point:

280.42°C (rough estimate)

Density 

1.1832 (rough estimate)

refractive index 

1.4880 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

pka

13.12±0.40(Predicted)

optical activity

[α]20/D 31.5°, c = 1 in H2O

Water Solubility 

23 g/L (22 ºC)

BRN 

82869

InChI

InChI=1S/C7H12N2O2/c1-4(2)6-7(11)8-3-5(10)9-6/h4,6H,3H2,1-2H3,(H,8,11)(H,9,10)/t6-/m1/s1

InChIKey

IULFBTHVPRNQCG-ZCFIWIBFSA-N

SMILES

N1CC(=O)N[C@H](C(C)C)C1=O

Safety Information

Hazard Codes 

Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

22-24/25-36/37/39-26

WGK Germany 

3

F 

3-10

HS Code 

29335995

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

(R)-3-Isopropyl-2,5-piperazinedione Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

(R)-3-Isopropyl-2,5-piperazinedione acts as a useful reagent in the synthesis of (R)-2,5-dihydro-3,6-dimethoxy-2-isopropylpyrazine.

Uses

Chiral auxiliary developed by Professor Sch?llkopf for the enantioselective synthesis of α-amino acids.

(R)-3-Isopropyl-2,5-piperazinedione(143673-66-9)Related Product Information

• L-Valine
• Diisopropylamine
• Cumene
• Isopropyl alcohol
• N,N-Diisopropylethylamine
• ISOPROPYL LAURATE
• 3-Methyl-2-butanone
• (2R)-2-[(4-Ethyl-2,3-dioxopiperazinyl)carbonylamino]-2-(4-hydroxyphenyl)acetic acid
• Cuminaldehyde
• (S)-3-ISOPROPYL-2,5-PIPERAZINEDIONE,(S)-3-ISOPROPYL-2 5-PIPERAZINEDIONE 99%
• (S)-N,N'-Bis(p-methoxybenzyl)-3-isopropyl-piperazine-2,5-dione
• (R)-(-)-2-Methylpiperazine
• (R)-N,N'-Bis(p-methoxybenzyl)-3-isopropyl-piperazine-2,5-dione
• GLYCYL-D-VALINE
• Piperazine
• (R)-2-ETHYL-PIPERAZINE
• R-2-ISOPROPYL-PIPERAZINE
• 3-ISOPROPYL-PIPERAZIN-2-ONE