ChemicalBook > Product Catalog > API > Hormones and the Endocrine System > Contraceptives > Gossypol-acetic acid
Gossypol-acetic acid
Gossypol-acetic acid Basic information
- Product Name:
- Gossypol-acetic acid
- Synonyms:
-
- (±)-Gossypol-acetic aci
- acetic acid gossypol 12542-36-8
- GOSSYPOLACETATE(GOSSYPOL-ACETICACID)
- GOSSYPOL ACETATE(RG)
- Acetate gossypol
- Gossypol-acetic acid 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)[2,2'-binaphthalene]-8,8'-dicarboxaldehyde-acetic acid
- Gossypol-acetic acid, >=98%
- Cottonseed extract
- CAS:
- 12542-36-8
- MF:
- C32H34O10
- MW:
- 578.61
- EINECS:
- 623-939-3
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- API
- Inhibitors
- Aromatic Phenols
- Mol File:
- 12542-36-8.mol
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Gossypol-acetic acid Chemical Properties
- Melting point:
- 164-168°C
- storage temp.
- −20°C
- solubility
- Soluble in acetone or methanol at 5mg/ml
- form
- Solid
- color
- Yellow to Very Dark Yellow
- InChIKey
- NIOHNDKHQHVLKA-UHFFFAOYSA-N
- SMILES
- C12C(C(C)C)=C(C(O)=C(C=O)C=1C(O)=C(C1C(C)=CC3C(C(C)C)=C(O)C(O)=C(C=O)C=3C=1O)C(C)=C2)O.C(=O)(O)C
- LogP
- 6.157 (est)
- CAS DataBase Reference
- 12542-36-8(CAS DataBase Reference)
- EPA Substance Registry System
- Gossypol acetic acid (12542-36-8)
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MSDS
- Language:English Provider:SigmaAldrich
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Gossypol-acetic acid Usage And Synthesis
Chemical Properties
Derived from the seeds and root bark of Gossypium herbaceum L., a plant of the Malvaceae family
Uses
Gossypol is a mixture of natural polyphenols isolated from the cotton plant. It causes spermatogenesis arrest in humans and also functions as an anti-malarial agent. Antiinflammatory. Anticancer.
Biochem/physiol Actions
Reported to inhibit the autolytic conversion of pepsinogen to pepsin.
IC 50
Bcl-xL: 0.5-0.6 μM (Ki); Bcl-2: 0.2-0.3 mM (Ki)
Gossypol-acetic acidSupplier
Nanjing Sunlida Biological Technology Co., Ltd. Gold
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