DESMETHYLDOXEPIN Chemical Properties

Melting point:

63-65℃

Boiling point:

408.57°C (rough estimate)

Density 

1.0629 (rough estimate)

refractive index 

1.5100 (estimate)

Flash point:

9℃

storage temp. 

-20°C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

pKa 9.75(I=0.00 t=25.0) (Uncertain)

color 

White

Water Solubility 

104.8mg/L(25 ºC)

EPA Substance Registry System

1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N-methyl- (1225-56-5)

Safety Information

Hazard Codes 

F,T

Risk Statements 

11-23/24/25-39/23/24/25

Safety Statements 

7-16-36/37-45

RIDADR 

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany 

2

DESMETHYLDOXEPIN Usage And Synthesis

Uses

Desmethyldoxepin solution may be used as an internal standard in the high performance liquid chromatographic (HPLC) determination of bupivacaine in samples of human serum.

Definition

ChEBI: (E)-desmethyldoxepin is the (E)-isomer of desmethyldoxepin.

General Description

Desmethyldoxpein is the primary urinary metabolite of doxepin, a tricyclic antidepressant used for the treatment of sleep maintenance and sold under trade names such as Silenor^? and Aponal. This analytical reference standard is suited for use in LC/MS or GC/MS methods for urine drug testing, clinical toxicology, and forensic analysis applications.

DESMETHYLDOXEPIN(1225-56-5)Related Product Information

• DOXEPIN
• Doxepin hydrochloride
• DESMETHYLDOXEPIN
• DOXEPIN
• CIS,TRANS-DOXEPIN-D3
• 11[6H]-[3-(METHYLAMINO)PROPYLIDENE]DIBENZ[B,E]OXEPINE HYDROCHLORIDE