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METHYSTICIN

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METHYSTICIN Basic information

Product Name:
METHYSTICIN
Synonyms:
  • (R)-6-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one
  • d-Methysticin
  • METHYLSTICIN
  • (6R)-6-[(E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one
  • (+)-Methysticin
  • R-(+)-Methysticin
  • NF-κB Activation Inhibitor X, Methysticin
  • (r-(e))-6-(2-(1,3-benzodioxol-5-yl)ethenyl)-5,6-dihydro-4-methoxy-2h-pyran-2
CAS:
495-85-2
MF:
C15H14O5
MW:
274.27
Product Categories:
  • Coumarins
  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Mutagenesis Research Chemicals
Mol File:
495-85-2.mol
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METHYSTICIN Chemical Properties

Melting point:
132-134°
Boiling point:
337.26°C (rough estimate)
Density 
1.1827 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
2-8°C
solubility 
DMF: 2.5 mg/ml; DMSO: 5 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml; Ethanol: 1 mg/ml
form 
White solid
color 
White to off-white
optical activity
[α]/D 118±2°, c = 0.1 in dichloromethane
BRN 
91701
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Safety Information

WGK Germany 
3
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METHYSTICIN Usage And Synthesis

Uses

A lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. One of the active components of the intoxicating beverage Kava from the Pacific Islands.

Definition

ChEBI: Methysticin is a member of 2-pyranones and an aromatic ether.

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