19-HYDROXY-4-ANDROSTENE-3,17-DIONE
19-HYDROXY-4-ANDROSTENE-3,17-DIONE Basic information
- Product Name:
- 19-HYDROXY-4-ANDROSTENE-3,17-DIONE
- Synonyms:
-
- 19-HYDROXY-4-ANDROSTEN-3,17-DIONE
- 19-HYDROXY-4-ANDROSTENE-3,17-DIONE
- 19-HYDROXYANDROSTENDIONE
- 19-HYDROXYANDROSTENEDIONE
- Androst-4-ene-3,17-dione, 19-hydroxy-
- 19-hydroxyandrost-4-ene-3,17-dione
- 4-ANDROSTENE-3,17-DIONE-19-0L
- 4-ANDROSTENE-3,17-DIONE-19-OL
- CAS:
- 510-64-5
- MF:
- C19H26O3
- MW:
- 302.41
- EINECS:
- 208-116-5
- Product Categories:
-
- All Inhibitors
- Inhibitors
- Steroids
- Mol File:
- 510-64-5.mol
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19-HYDROXY-4-ANDROSTENE-3,17-DIONE Chemical Properties
- Melting point:
- 168-169 °C(lit.)
- Boiling point:
- 485.4±45.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 14.90±0.10(Predicted)
- color
- Off-White to Pale Yellow
- optical activity
- [α]/D +190±5°, c = 1 in chloroform
- BRN
- 2567249
- CAS DataBase Reference
- 510-64-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 19-Hydroxyandrost-4-ene-3,17-dione(510-64-5)
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Safety Information
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-63
- Safety Statements
- 22-24/25-36/37/39-27-26-36/37
- WGK Germany
- 3
- HS Code
- 29372900
MSDS
- Language:English Provider:SigmaAldrich
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19-HYDROXY-4-ANDROSTENE-3,17-DIONE Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
19-Hydroxyandrostendione is a novel substituted estrogen as aromatase inhibitor. It induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olactory receptor.
Definition
ChEBI: 19-hydroxyandrost-4-ene-3,17-dione is a 19-hydroxy steroid, a 3-oxo steroid, a 17-oxo steroid and an androstanoid. It has a role as a mouse metabolite.
Purification Methods
Recrystallise 19-hydroxy-4-androsten-3,17-dione from Me2CO/hexane or Et2O/hexane. It has UV with max at 242nm in EtOH or MeOH. The 19-acetoxy derivative has [] 26D +185o (CHCl3) and max 237.5nm in EtOH. [Ehrenstein & Dünnenberger J Org Chem 21 774 1956, Beilstein 8 IV2162.]
19-HYDROXY-4-ANDROSTENE-3,17-DIONE Preparation Products And Raw materials
Raw materials
19-HYDROXY-4-ANDROSTENE-3,17-DIONESupplier
J & K SCIENTIFIC LTD.
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Energy Chemical
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- 021-021-58432009 400-005-6266
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JinYan Chemicals(ShangHai) Co.,Ltd.
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- 13817811078
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Nanjing Chemlin Chemical Co., Ltd
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Chemsky（shanghai）International Co.,Ltd.
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- 021-50135380
- shchemsky@sina.com
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19-HYDROXY-4-ANDROSTENE-3,17-DIONE(510-64-5)Related Product Information
- Dienogest Impurity I
- (17α)-3,3-[1,2-Ethanediylbis(oxy)]-17-hydroxy-19-norpregna-5(10),9(11)-diene-21-nitrile
- DiMethoxy Dienogest
- 9,11-Dehydro-17α-cyanoMethyl Estradiol
- Dienogestrel
- Sts 64
- (17α)-17-Hydroxy-3-oxo-19-norpregna-5(10),9(11)-diene-21-nitrile
- 3,3-DiMethoxyestra-5(10),9(11)-dien-17-one
- 17 alpha-cyanomethyl-19-nortestosterone
- (17α)-4-Bromo-17-hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile
- Estra-4,9-diene-3,17-dione
- Estradiene dione-3-keta
- 17β-Cyanmethyl-oestra-1,3,5(10)-trien-3,17β-diol
- 11β-Hydroperoxy Dienogest
- ISOPROPYLCYCLOHEXANE
- Naphthalene,1-butyldecahydro-
- TRANS-DECAHYDRONAPHTHALENE
- 3,3-DIMETHYL-1-PENTENE