Basic information Safety Supplier Related

19-HYDROXY-4-ANDROSTENE-3,17-DIONE

Basic information Safety Supplier Related

19-HYDROXY-4-ANDROSTENE-3,17-DIONE Basic information

Product Name:
19-HYDROXY-4-ANDROSTENE-3,17-DIONE
Synonyms:
  • 19-HYDROXY-4-ANDROSTEN-3,17-DIONE
  • 19-HYDROXY-4-ANDROSTENE-3,17-DIONE
  • 19-HYDROXYANDROSTENDIONE
  • 19-HYDROXYANDROSTENEDIONE
  • Androst-4-ene-3,17-dione, 19-hydroxy-
  • 19-hydroxyandrost-4-ene-3,17-dione
  • 4-ANDROSTENE-3,17-DIONE-19-0L
  • 4-ANDROSTENE-3,17-DIONE-19-OL
CAS:
510-64-5
MF:
C19H26O3
MW:
302.41
EINECS:
208-116-5
Product Categories:
  • All Inhibitors
  • Inhibitors
  • Steroids
Mol File:
510-64-5.mol
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19-HYDROXY-4-ANDROSTENE-3,17-DIONE Chemical Properties

Melting point:
168-169 °C(lit.)
Boiling point:
485.4±45.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
14.90±0.10(Predicted)
color 
Off-White to Pale Yellow
optical activity
[α]/D +190±5°, c = 1 in chloroform
BRN 
2567249
CAS DataBase Reference
510-64-5(CAS DataBase Reference)
NIST Chemistry Reference
19-Hydroxyandrost-4-ene-3,17-dione(510-64-5)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-63
Safety Statements 
22-24/25-36/37/39-27-26-36/37
WGK Germany 
3
HS Code 
29372900

MSDS

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19-HYDROXY-4-ANDROSTENE-3,17-DIONE Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

19-Hydroxyandrostendione is a novel substituted estrogen as aromatase inhibitor. It induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olactory receptor.

Definition

ChEBI: 19-hydroxyandrost-4-ene-3,17-dione is a 19-hydroxy steroid, a 3-oxo steroid, a 17-oxo steroid and an androstanoid. It has a role as a mouse metabolite.

Purification Methods

Recrystallise 19-hydroxy-4-androsten-3,17-dione from Me2CO/hexane or Et2O/hexane. It has UV with max at 242nm in EtOH or MeOH. The 19-acetoxy derivative has [] 26D +185o (CHCl3) and max 237.5nm in EtOH. [Ehrenstein & Dünnenberger J Org Chem 21 774 1956, Beilstein 8 IV2162.]

19-HYDROXY-4-ANDROSTENE-3,17-DIONE Preparation Products And Raw materials

Raw materials

19-HYDROXY-4-ANDROSTENE-3,17-DIONESupplier

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