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STACHYOSE

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STACHYOSE Basic information

Product Name:
STACHYOSE
Synonyms:
  • STACHYOSE N-HYDRATE
  • STACHYOSE
  • Lupeose, α-D-Gal-(1-6)-α-D-Gal-(1-6)-α-D-Glc-(1-2)-β-D-Fru, β-D-Fructofuranosyl-O-α-D-galactopyranosyl-(1-6)-O-α-D-galactopyranosyl-(1-6)-α-D-glucopyranoside
  • MANNOTETRAOSE
  • LUPEOSE
  • Stachyose hydrate,98.5%
  • beta-D-Fructofuranosyl O-alpha-D-Galactopyranosyl-(1-6)-O-alpha-D-galactopyranosyl-(1-6)-alpha-D-glucopyranoside Lupeose Manneotetrose
  • Stachyose hydrate, 97+%
CAS:
54261-98-2
MF:
C24H44O22
MW:
684.59
EINECS:
207-427-3
Mol File:
54261-98-2.mol
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STACHYOSE Chemical Properties

Melting point:
110 °C(dec.)
storage temp. 
-20°C
Water Solubility 
Soluble in water
solubility 
DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
form 
Liquid
color 
Clear colorless to yellow to pale brown, may darken during storage
biological source
plant (Stachys tuberifera)
optical activity
[α]24/D +133°, c = 4 in H2O
BRN 
5710666
Stability:
Hygroscopic
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29400090
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STACHYOSE Usage And Synthesis

Uses

Stachyose Hydrate is a low molecular weight carbohydrate that was separated through an EM Gel OR-PVA column.

Biological Activity

Stachyose belongs to the raffinose family of oligosaccharides (RFOs)

in vivo

Stachyose hydrate (200, 400, 600 mg/kg, p.o., once daily for 3 weeks) alleviates colitis symptoms, restores intestinal barrier integrity, and modulates pro-inflammatory and anti-inflammatory cytokine expression in DSS (HY-116282C)-induced ulcerative colitis C57BL/6J mice[2].

Animal Model:DSS (HY-116282C)-induced ulcerative colitis C57BL/6J mouse model[2]
Dosage:200, 400, 600 mg/kg
Administration:Oral gavage (p.o.), once daily for 3 weeks
Result:Significantly alleviated colitis symptoms in DSS-induced colitis mice, including reducing weight loss, lowering disease activity index (DAI), and increasing colon length, while restoring colonic epithelial barrier integrity. Dose-dependently upregulated mRNA expression of ZO-1, Claudin-1, and Occludin, reduced IL-17, TNF-α, IL-1β, and IL-6 expression, and increased IL-10 levels.

IC 50

Human Endogenous Metabolite

STACHYOSESupplier

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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Beijing HwrkChemical Technology Co., Ltd
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18515581800 18501085097
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sales.bj@hwrkchemical.com
Energy Chemical
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021-021-58432009 400-005-6266
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sales8178@energy-chemical.com
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