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2-Amino-5-fluoropyridine

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2-Amino-5-fluoropyridine Basic information

Product Name:
2-Amino-5-fluoropyridine
Synonyms:
  • 5-FLUORO-2-PYRIDINAMINE
  • 5-FLUOROPYRIDIN-2-AMINE
  • 5-FLUORO-PYRIDIN-2-YL-AMINE
  • 5-FLUORO-2-AMINOPYRIDINE
  • 2-Amino-5-fluoroypyridine
  • 2-Amino-5-fluoropyridine 95%
  • 2-Amino-5-fluoropyridine95%
  • 2-AMINO-5-FLUOROPYRIDINE, 98+%
CAS:
21717-96-4
MF:
C5H5FN2
MW:
112.11
EINECS:
627-638-8
Product Categories:
  • Boronic Acid
  • C5
  • blocks
  • Heterocyclic Building Blocks
  • Amino-pyridine series
  • Fluorine series
  • Fluorin-contained pyridine series
  • FluoroCompounds
  • Heterocycles
  • Pyridines
  • Pyridine
  • Pyridine series
  • Pyridines derivates
  • Fluoropyridines
  • Halopyridines
Mol File:
21717-96-4.mol
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2-Amino-5-fluoropyridine Chemical Properties

Melting point:
93-97 °C (lit.)
Boiling point:
125 °C
Density 
1.257±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
pka
4.62±0.13(Predicted)
form 
Powder
color 
White to orange
BRN 
385938
InChI
InChI=1S/C5H5FN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
InChIKey
YJTXQLYMECWULH-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(F)C=C1
CAS DataBase Reference
21717-96-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,C
Risk Statements 
36/37/38-34
Safety Statements 
26-36-45-36/37/39-27
RIDADR 
UN2811
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
II
HS Code 
29333999

MSDS

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2-Amino-5-fluoropyridine Usage And Synthesis

Chemical Properties

Light yellow Cryst

Uses

2-Amino-5-fluoropyridine is used in chemical microarrays to identify ligands that binds pathogenic cells. Acts as a reagent in the preparation of heterocyclic compounds as integrase inhibiting antiviral agents.

Definition

ChEBI: 2-Amino-5-fluoropyridine is a dihydropyridine.

Synthesis

2-Amino-5-fluoropyridine is an important intermediate for the synthesis of LBM415 which is the peptide deformylas inhibitor. Using 2-aminopyridine as raw material and via nitrification, amino acetylation, reduction of nitro, diazolization, Schiemann reaction and hydrolysis of acetyl.

2-Amino-5-fluoropyridine Preparation Products And Raw materials

Raw materials

2-Amino-5-fluoropyridineSupplier

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