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5-Nitroanthranilonitrile

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5-Nitroanthranilonitrile Basic information

Product Name:
5-Nitroanthranilonitrile
Synonyms:
  • 2-Cyan-4-nitroaniline
  • 2-cyano-4-nitro-anilin
  • 2-kyan-4-nitroanilin
  • 5-NITROANTHRANILONITRILE
  • 5-nitro-anthranilonitril
  • 2-amino-5-nitro-benzonitril
  • 2-CYANO-4-NITROANILINE
  • 2-AMINO-5-NITROBENZONITRILE
CAS:
17420-30-3
MF:
C7H5N3O2
MW:
163.13
EINECS:
241-446-8
Product Categories:
  • Aromatic Nitriles
  • Building Blocks
  • C6 to C7
  • Chemical Synthesis
  • Cyanides/Nitriles
  • Nitrogen Compounds
  • Organic Building Blocks
  • john's
Mol File:
17420-30-3.mol
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5-Nitroanthranilonitrile Chemical Properties

Melting point:
200-207 °C(lit.)
Boiling point:
290.19°C (rough estimate)
Density 
1.4141 (rough estimate)
refractive index 
1.5500 (estimate)
Flash point:
234 °C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly)
form 
Solid
pka
-1.97±0.10(Predicted)
color 
Dark Yellow
BRN 
1425714
CAS DataBase Reference
17420-30-3(CAS DataBase Reference)
EPA Substance Registry System
Benzonitrile, 2-amino-5-nitro- (17420-30-3)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
22-24/25-36-26
WGK Germany 
2
RTECS 
BX2500000
TSCA 
Yes
HS Code 
29269090
Toxicity
mouse,LD50,oral,6710mg/kg (6710mg/kg),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(1), Pg. 50, 1986.

MSDS

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5-Nitroanthranilonitrile Usage And Synthesis

Chemical Properties

yellow to brownish powder. 2-Amino-5-nitrobenzonitrile [17420-30-3], 2-cyano-4-nitroaniline, Mr 163.13, mp 210℃, is readily soluble in acetone, chloroform, and benzene; it is sparingly soluble in water and ethanol. As already mentioned, the reaction of 2-chloro5-nitrobenzonitrile with ammonia gives 2-amino-5-nitrobenzonitrile, an intermediate for azo dyes.

Production Methods

A newer synthetic route starts from 6-nitroisatoic anhydride [2H-3,1-benzoxazine-6-nitro-2,4 (1H)-dione]: the latter is converted into 2-amino-5-nitrobenzonitrile by reaction with ammonia, subsequent treatment with phosgene in dimethylformamide or Nmethylpyrrolidone, followed by hydrolysis of the formamidine.

Synthesis Reference(s)

Journal of the American Chemical Society, 82, p. 3152, 1960 DOI: 10.1021/ja01497a043

5-Nitroanthranilonitrile Preparation Products And Raw materials

Raw materials

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