Basic information Safety Supplier Related

DBCO-PEG3-amine

Basic information Safety Supplier Related

DBCO-PEG3-amine Basic information

Product Name:
DBCO-PEG3-amine
Synonyms:
  • DBCO-PEG3-amine
  • DBCO-PEG3-amine,DBCO-PEG3-NH2
  • Dibenz[b,f]azocine-5(6H)-butanamide, N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-11,12-didehydro-γ-oxo-
  • N-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]-11,12-didehydro-γ-oxo-Dibenz[b,f]azocine-5(6H)-butanamide
  • DBCO-PEG3-amine (contains 5% Acetonitrile at maximum)
CAS:
2093409-57-3
MF:
C27H33N3O5
MW:
479.58
Mol File:
2093409-57-3.mol
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DBCO-PEG3-amine Chemical Properties

Boiling point:
765.8±60.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
pka
15.14±0.46(Predicted)
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DBCO-PEG3-amine Usage And Synthesis

Uses

DBCO-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG3-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-PEG3-amineSupplier

Shanghai Macklin Biochemical Co.,Ltd.
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15221275939
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Xi'an Confluore Biological Technology Co., Ltd.
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Zhengzhou Acme Chemical Co., Ltd.
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Alfa Chemistry
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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13892832556
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DBCO-PEG3-amine(2093409-57-3)Related Product Information