Cystamine dihydrochloride Chemical Properties

Melting point:

217-220 °C (dec.)(lit.)

storage temp. 

Store below +30°C.

solubility 

H2O: soluble1.0g/10 mL, clear to almost clear, colorless to almost colorless (<5.5 NTU)

form 

Crystalline Powder, Crystals or Chunks

color 

White to yellow

Water Solubility 

soluble

Sensitive 

Hygroscopic

Merck 

14,2776

BRN 

3616850

Stability:

Stable. Incompatible with strong oxidizing agents.

CAS DataBase Reference

56-17-7(CAS DataBase Reference)

EPA Substance Registry System

Ethanamine, 2,2'-dithiobis-, dihydrochloride (56-17-7)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

37/39-26-36/37/39

WGK Germany 

3

RTECS 

KR7260000

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29309070

MSDS

• Language:English Provider:2,2'-Dithiodi(ethylammonium) dichloride
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Cystamine dihydrochloride Usage And Synthesis

Chemical Properties

white powder

Uses

hepatoprotectant, t-glutaminase inhibitor, heat shock protein promoter, caspase inhibitor

Uses

sulfhydryl modifying reagent and heparin antagonist

Uses

Cystamine dihydrochloride acts as an anti-infective agent, which is used in the treatment of urinary tract infections. It is also used as a radiation-protective agent that interferes with sulfhydryl enzymes. Further, it serves as a heparin antagonist and sulfhydryl modifying reagent. In addition to this, it is used as an inhibitor of TGase.

Safety Profile

A poison by subcutaneous and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of HCl, SOx, and NOx. See also SULFIDES.

storage

room temperature (desiccate)

Purification Methods

Recrystallise the salt by dissolving in EtOH containing a few drops of dry EtOH/HCl, filtering and adding dry Et2O. The solid is dried in a vacuum and stored in a dry and dark atmosphere. It has been recrystallised from EtOH (solubility: 1g in 60mL of boiling EtOH) or MeOH (plates). The free base has b 90-Purification of Biochemicals — Amino Acids and Peptides 100o/0.001mm, 106-108o/5mm and 135-136o/760mm, d 4 1.1559, n D 1.5720. [Verly & Koch Biochem J 58 663 1954, Gonick et al. J Am Chem Soc 76 4671 1954, Jackson & Block J Biol Chem 113 137 1936.] The dihydrobromide has m 238-239o (from EtOH/Et2O) [Viscontini Helv Chim Acta 36 835 1953]. [Beilstein 4 H 287, 4 IV 1578.]

Cystamine dihydrochloride(56-17-7)Related Product Information

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