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(4S-TRANS)-2 2-DIMETHYL-A A A' A'-TETRA&

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(4S-TRANS)-2 2-DIMETHYL-A A A' A'-TETRA& Basic information

Product Name:
(4S-TRANS)-2 2-DIMETHYL-A A A' A'-TETRA&
Synonyms:
  • [(4S,5S)-5-[hydroxy(dinaphthalen-1-yl)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl]-dinaphthalen-1-ylmethanol
  • (4S-TRANS)-2 2-DIMETHYL-A A A' A'-TETRA&
  • (4S-TRANS)-2,2-DIMETHYL-A,A,A',A'-TETRA( 1-NAPHTHYL)-1,3-DIOXOLANEDIMETHANOL, 99%
  • (4s-trans)-2,2-dimethyl-α,α,α',α'-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol
  • (4S,5S)-2,2-Dimethyl-alpha,alpha,alpha',alpha'-tetra(1-nephthyl)-1,3-dioxolane-4,5-dimethanol
  • (4S-trans)-2,2-Dimethyl-alpha,alpha,alpha',alpha'-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol 99%
  • (4S,5S)-2,2-dimethyl-α4,α4,α5,α5-tetra-1-naphthalenyl-1,3-Dioxolane-4,5-dimethanol
  • (4S,5S)-(-)-2,2-Dimethyl-α,α,α',α'-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol,98%
CAS:
171086-52-5
MF:
C47H38O4
MW:
666.8
Product Categories:
  • Chiral Oxygen
  • TADDOL Series
  • Chiral Catalysts, Ligands, and Reagents
  • Privileged Ligands and Complexes
  • TADDOLs
Mol File:
171086-52-5.mol
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(4S-TRANS)-2 2-DIMETHYL-A A A' A'-TETRA& Chemical Properties

Melting point:
200 °C (dec.)(lit.)
Density 
1.269±0.06 g/cm3(Predicted)
pka
12.00±0.29(Predicted)
optical activity
[α]20/D +280°, c = 1 in ethyl acetate
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Safety Information

WGK Germany 
3
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(4S-TRANS)-2 2-DIMETHYL-A A A' A'-TETRA& Usage And Synthesis

Uses

(4S-trans)-2,2-Dimethyl-α,α,α′,α′-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol, also known as TADDOL, is a chiral auxiliary that can be used:

  • For the highly enantioselective addition of primary alkyl Grignards to ketones.
  • As an organocatalyst for the activation of carbonyl functionality in vinylogous addition reaction of an aldehyde.
  • As a chiral dopant in the preparation of cholesteric liquid crystal (CLC) having an aggregation-induced-emission dye.

(4S-TRANS)-2 2-DIMETHYL-A A A' A'-TETRA&Supplier

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