PEPTIDE YY, PORCINE
PEPTIDE YY, PORCINE Basic information
- Product Name:
- PEPTIDE YY, PORCINE
- Synonyms:
-
- Peptide YY porcine, ≥97% (HPLC)
- Peptide YY (Canis familiaris intestine)
- Peptide YY (pig)
- Peptide YY (rat)
- Porcine peptide YY
- Rat peptide YY
- PeptideYY (swine) (9CI)
- M.W. 4240.65 C190H288N54O57
- CAS:
- 81858-94-8
- MF:
- C190H288N54O57
- MW:
- 4240.7
- Product Categories:
-
- Peptide
- Neuropeptide Y (NPY ) receptor
- Mol File:
- Mol File
PEPTIDE YY, PORCINE Chemical Properties
- storage temp.
- −20°C
PEPTIDE YY, PORCINE Usage And Synthesis
Uses
Peptide YY (pig) is a 36 amino acid gastrointestinal peptide, can be isolated from porcine duodenum. Peptide YY (pig) decreases appetite and food-intake by activation of the Y2 receptor. Peptide YY (pig) is present mainly in pancreatic endocrine cells with effect on both intestinal motility and the cardiovascular system[1][2][3].
in vivo
Peptide YY1-36 (pig) is degraded to PYY3-36 by dipeptidyl peptidase IV (DPP-IV), and PYY3-36 (50 nmol/kg; i.v.; single dose) is further broken down into many metabolism in G?ttingen mini-pig and Rhesus monkey[3].
Peptide YY1-36 (pig) shows other physiological effects including slowing of intestinal transit, inhibition of gastrointestinal anion and electrolyte secretion and lowering of blood glucose[3].
IC 50
NPY Y2 receptor
References
[1] Lundberg JM, et al. Localization of peptide YY (PYY) in gastrointestinal endocrine cells and effects on intestinal blood flow and motility. Proc Natl Acad Sci U S A. 1982 Jul;79(14):4471-5. DOI:10.1073/pnas.79.14.4471
[2] Ding WG, et al. Neuropeptide Y and peptide YY immunoreactivities in the pancreas of various vertebrates. Peptides. 1997;18(10):1523-9. DOI:10.1016/s0196-9781(97)00237-4
[3] Olsen J, et al. Metabolism of peptide YY 3-36 in G?ttingen mini-pig and rhesus monkey. Peptides. 2016 Apr;78:59-67. DOI:10.1016/j.peptides.2016.01.010
PEPTIDE YY, PORCINESupplier
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PEPTIDE YY, PORCINE(81858-94-8)Related Product Information
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- PHENYLSELENOL
- METHYL ISOCYANOACETATE
- 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
- Tosylmethyl isocyanide
- SALCOMINE
- TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
- DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
- Benzyl isocyanide
- 2,4-PENTANEDIONE, SILVER DERIVATIVE
- TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
- TERT-BUTYL ISOCYANIDE
- COBALT(II) ACETYLACETONATE
- Tris(2,4-pentanedionato)chroMiuM(III)