Chlorhexidine diacetate
Chlorhexidine diacetate Basic information
- Product Name:
- Chlorhexidine diacetate
- Synonyms:
-
- Chlorhexidine (acetate hydrate)
- 2-[N'-[6-[[Amino-[[amino-[(4-chlorophenyl)amino]methylidene]amino]methylidene]amino]hexyl]carbamimidoyl]-1-(4-chlorophenyl)guanidine diacetate
- Chlorhexidine diacetate
- CHLORHEXIDINE DIACETATE HYDRATE, 98
- 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(4-chlorophenyl)-3,12-diimino-, acetate, hydrate (1:2:)
- Chlorhexidine acetate hydrate(1:2:x)
- TIANFU CHEM--Chlorhexidine diacetate
- 2,4,11,13-Tetraazatetradecanediimidamide,N,N''-bis(4-chlorophenyl)-3,12-diimino-,diacetate,hydrate
- CAS:
- 206986-79-0
- MF:
- C22H30Cl2N10.2C2H4O2.xH2O
- MW:
- 625.55
- EINECS:
- 205-516-1
- Mol File:
- 206986-79-0.mol
Chlorhexidine diacetate Chemical Properties
- Melting point:
- 153-157°C
- storage temp.
- room temp
- solubility
- DMF: 15 mg/mL; DMSO: 15 mg/mL; DMSO:PBS(pH 7.2) (1:2): 0.33 mg/mL; Ethanol: 10 mg/mL
- form
- Powder
- color
- White to almost white
- InChI
- InChI=1S/C22H30Cl2N10.C2H4O2/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;1-2(3)4/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);1H3,(H,3,4)
- InChIKey
- STXIUCWIIZWUGG-UHFFFAOYSA-N
- SMILES
- N(C1C=CC(Cl)=CC=1)C(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1C=CC(Cl)=CC=1.C(=O)(O)C
Chlorhexidine diacetate Usage And Synthesis
Chemical Properties
white to almost white powder
Uses
Antipsychotic
Uses
Chlorhexidine Diacetate is an antimicrobial dental impression materials.
Definition
ChEBI: Chlorhexidine acetate is the acetate salt of chlorhexidine. It is a disinfectant used for bacterial control in hospital, agricultural and domestic environments. It has a role as an antibacterial agent, an antiinfective agent, an antifungal agent and an antifouling biocide. It contains a chlorhexidine.
Biochem/physiol Actions
Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective against both Gram-positive and Gram-negative bacteria. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.
in vivo
| Animal Model: | One hundred and eighty male Imprinting Control Region (ICR) mice at 6 to8-wk-old (body weight, 25 ± 3 g) were randomized to six groups[1]. |
| Dosage: | Chlorhexidine gluconate 0.05%, and Chlorhexidine gluconate 0.025%. |
| Administration: | One-time intraperitoneal injection. |
| Result: | A total of 48 mice (26.7%) developed postoperative intra-abdominal abscesses. Mice that had Chlorhexidine gluconate 0.05% lavage had significantly lower incidence of postoperative intra-abdominal abscesses compared with that of group D mice that had saline lavage only (P = 0.0113). Microscopic peritoneal fibrosis occurred significantly more among group E mice that had Chlorhexidine gluconate 0.05% lavage compared with group D mice that had saline lavage only (P = < 0.005). |
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Chlorhexidine diacetate(206986-79-0)Related Product Information
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