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MESO-2 3-DIAMINOSUCCINIC ACID

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MESO-2 3-DIAMINOSUCCINIC ACID Basic information

Product Name:
MESO-2 3-DIAMINOSUCCINIC ACID
Synonyms:
  • erythro-3-aminoaspartic acid
  • (2R,3S)-diaminosuccinic acid
  • (2R,3S)-2,3-Diaminosuccinic acid
  • (3R)-3-Amino-L-aspartic acid
  • Einecs 245-500-1
  • D-Aspartic acid, 3-amino-, (3S)-rel-
  • (2R,3S)-2,3-Diaminosuccinicaci
  • MESO-2 3-DIAMINOSUCCINIC ACID USP/EP/BP
CAS:
23220-52-2
MF:
C4H8N2O4
MW:
148.12
EINECS:
245-500-1
Product Categories:
  • Others
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • amino
Mol File:
23220-52-2.mol
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MESO-2 3-DIAMINOSUCCINIC ACID Chemical Properties

Melting point:
304 °C
Boiling point:
304.7±42.0 °C(Predicted)
Density 
1.611±0.06 g/cm3(Predicted)
pka
1.43±0.27(Predicted)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29214900
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MESO-2 3-DIAMINOSUCCINIC ACID Usage And Synthesis

Uses

meso-2,3-Diaminosuccinic Acid is used as a building block in organic synthesis. As well as used in the synthesis of metal complexes for antitumor activity.

Purification Methods

Crystallise the acid from water. Also, dissolve it in dilute NaOH and add AcOH to pH 5-6 and allow it to crystallise (m 304o dec). Alternatively dissolve the acid in aqueous NH3 and boil; when the NH3 has evaporated, the acid separates, filter it off and dry it at room temperature in a vacuum. In another procedure 1g of acid is dissolved in 10mL of conc HCl + 15mL of H2O at 80o, filter immediately, dilute with 20mL of H2O and allow to stand for 24hours. When the monohydrochloride (0.7g, m 175-156o dec) crystallises out, filter and dry it. It has also been purified by dissolving it in the minimum volume of 10% HCl, filtering, and diluting with 5volumes of H2O when the crystals separate slowly on standing. The acid is filtered off after 24hours and dried (m 306-306o dec). Similar procedures were used for the dl-isomer. [Kenner J Org Chem 13 28 1948, McKennis & Yard J Org Chem 23 980 1958, Beilstein 4 III 1528, 4 IV 3025.]

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