MESO-2 3-DIAMINOSUCCINIC ACID Chemical Properties

Melting point:

304 °C

Boiling point:

304.7±42.0 °C(Predicted)

Density 

1.611±0.06 g/cm3(Predicted)

form 

powder

pka

1.43±0.27(Predicted)

color 

white

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

29214900

MESO-2 3-DIAMINOSUCCINIC ACID Usage And Synthesis

Uses

meso-2,3-Diaminosuccinic Acid is used as a building block in organic synthesis. As well as used in the synthesis of metal complexes for antitumor activity.

reaction suitability

reaction type: solution phase peptide synthesis

Purification Methods

Crystallise the acid from water. Also, dissolve it in dilute NaOH and add AcOH to pH 5-6 and allow it to crystallise (m 304o dec). Alternatively dissolve the acid in aqueous NH3 and boil; when the NH3 has evaporated, the acid separates, filter it off and dry it at room temperature in a vacuum. In another procedure 1g of acid is dissolved in 10mL of conc HCl + 15mL of H2O at 80o, filter immediately, dilute with 20mL of H2O and allow to stand for 24hours. When the monohydrochloride (0.7g, m 175-156o dec) crystallises out, filter and dry it. It has also been purified by dissolving it in the minimum volume of 10% HCl, filtering, and diluting with 5volumes of H2O when the crystals separate slowly on standing. The acid is filtered off after 24hours and dried (m 306-306o dec). Similar procedures were used for the dl-isomer. [Kenner J Org Chem 13 28 1948, McKennis & Yard J Org Chem 23 980 1958, Beilstein 4 III 1528, 4 IV 3025.]

MESO-2 3-DIAMINOSUCCINIC ACID(23220-52-2)Related Product Information

• Succinic acid
• DL-α,α'-diaminosuccinic acid