N-(TERT-BUTOXYCARBONYL)-2-BROMOANILINE Chemical Properties

Boiling point:

110 °C0.3 mm Hg(lit.)

Density 

1.342 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.54(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

pka

12.93±0.70(Predicted)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

N-(TERT-BUTOXYCARBONYL)-2-BROMOANILINE Usage And Synthesis

Uses

N-(tert-Butoxycarbonyl)-2-bromoaniline may be used in the synthesis of N-boc-protected o-aryl anilines, which undergoes coupling reaction with bromoacetylenes to form the corresponding arene?ynamides.

General Description

N-(tert-Butoxycarbonyl)-2-bromoaniline, also known as tert-butyl-N-(2-bromophenyl)carbamate, is an N-Boc-protected o-bromoaniline.1 It reacts with ethyl perfluorooctanoate in the presence of tert-butyllithium to form the corresponding 1-hydroxy-1H-perfluorooctyl compound.