ChemicalBook > Product Catalog > API > Synthetic Anti-infective Drugs > Quinolones > GATIFLOXACIN MESYLATE
GATIFLOXACIN MESYLATE
GATIFLOXACIN MESYLATE Basic information
- Product Name:
- GATIFLOXACIN MESYLATE
- Synonyms:
-
- AM 1155 mesylate
- AM 1155 MESYLATE;BMS 206584-01 MESYLATE;PD 135432 MESYLATE
- BMS 206584-01 mesylate
- Gatifloxacin mesylate (AM 1155 mesylate
- PD 135432 mesylate)
- GATIFLOXACIN MESYLATE
- 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-, MonoMethanesulfonate (9CI)
- GATIFLOXACIN MESYLATE USP/EP/BP
- CAS:
- 316819-28-0
- MF:
- C19H22FN3O4.CH4O3S
- MW:
- 471.503
- Mol File:
- 316819-28-0.mol
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GATIFLOXACIN MESYLATE Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Powder
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GATIFLOXACIN MESYLATE Usage And Synthesis
Uses
Gatifloxacin mesylate is a fourth generation fluoroquinolone antibiotic with broad-spectrum antibacterial activity. It is able to inhibit bacterial type II topoisomerase (IC50 = 13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA rotamase (IC50 = 0.109 μg/ml). It can be used to treat bacterial conjunctivitis in vivo, and its injection can treat acute urinary tract infections with efficacy comparable to levofloxacin hydrochloride injection[1].
References
[1] L. DENG. Observation on the curative effect of gatifloxacin mesylate injection in the treatment of acute urinary tract infections[J]. 国际医药卫生导报, 2009. DOI:10.3760/CMA.J.ISSN.1007-1245.2009.05.025.
GATIFLOXACIN MESYLATESupplier
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