CD46 antibody Usage And Synthesis

Applications

CD46 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Recommended starting dilution is 1:1000.

Immunogen

Anti-human CD46 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD46 protein 35-313 amino acids purified from E. coli.

Background

Membrane cofactor protein isoform 14 (CD46), is a type I membrane protein which has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1–4 vital for regulation. CD46 is also involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 is common in thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm.

CD46 antibody()Related Product Information

• ARHGEF2 antibody
• FAR2 antibody
• ASAH1 antibody
• BTN2A2 antibody
• TEKT4 antibody
• HOMER2 antibody
• CAPRIN1 Antibody
• UCHL5 antibody
• ARSG Antibody
• HSD17B12 antibody