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ChemicalBook >  Product Catalog >  Organic Chemistry >  Alcohols,Phenols,Phenol alcohols >  ((2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol

((2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol

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((2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol Basic information

Product Name:
((2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol
Synonyms:
  • 1H-Pyrrolizine-7a(5H)-methanol, 2-fluorotetrahydro-, (2R,7aS)-
  • ((2R,7aS)-2-Fluorohexahydro-1H-pyrrolizin-7a-yl)methanol
  • ((2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol
  • (2R,7aS)-2-fluorotetrahydro-1H-pyrrolizine-7a(5H)-methanol
  • (2R,7aS)-2-Fluorohexahydro-1H-pyrrolizine-7a-methanol
  • ((2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methano
  • ((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol C8H14FNO
CAS:
2097518-76-6
MF:
C8H14FNO
MW:
159.2
Mol File:
2097518-76-6.mol
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((2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol Chemical Properties

Boiling point:
225.6±15.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
pka
15.81±0.10(Predicted)
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((2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol Usage And Synthesis

Uses

((2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methanol, a "butterfly-shaped" bicyclic pyrrolidinol, is a key building block for drug candidates[1].

References

[1] Wenxing Guo and Cheng-yi Chen. “Practical Asymmetric Synthesis of a Bicyclic Pyrrolidinol.” Organic Process Research & Development 26 10 (2022): 2839–2846.

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