1-Ethyl-2-pyrrolidone Chemical Properties

Melting point:

87.5-88.5 °C

Boiling point:

97 °C/20 mmHg (lit.)

Density 

0.992 g/mL at 25 °C (lit.)

vapor pressure 

18Pa at 20℃

refractive index 

n20/D 1.465(lit.)

Flash point:

169 °F

storage temp. 

Sealed in dry,Room Temperature

pka

-0.41±0.20(Predicted)

form 

Liquid

color 

Clear

PH

8-9 (100g/l, H2O, 20℃)

explosive limit

1.3-7.7%(V)

Water Solubility 

1000g/L at 23℃

BRN 

107971

InChIKey

ZFPGARUNNKGOBB-UHFFFAOYSA-N

LogP

-0.2 at 20℃

CAS DataBase Reference

2687-91-4(CAS DataBase Reference)

NIST Chemistry Reference

1-Ethyl-2-pyrrolidinone(2687-91-4)

EPA Substance Registry System

2-Pyrrolidinone, 1-ethyl- (2687-91-4)

Safety Information

Hazard Codes 

Xn,T

Risk Statements 

22-36-62-41-61

Safety Statements 

26-36-45-36/37/39-53

WGK Germany 

1

RTECS 

UY5769250

TSCA 

Yes

HS Code 

29337900

MSDS

• Language:English Provider:1-Ethyl-2-pyrrolidinone
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

1-Ethyl-2-pyrrolidone Usage And Synthesis

Chemical Properties

N-Ethyl-2-pyrrolidone (NEP) is a colorless, clear liquid that serves as a low-volatility aprotic solvent classified as a reproductive toxicant. It is characterized by high solvency, low vapor pressure, and a low dielectric constant.

Uses

1-Ethyl-2-pyrrolidone was used to modify coir fiber (from Cocos nucifera) by photocuring.

Application

N-Ethyl-2-pyrrolidone is commonly used as a solvent. It has a low boiling point, which makes it suitable for use in low light and at constant pressure. It is also used as an intermediate in the preparation of polycarboxylic acid. It has been shown to be involved in both viscosity and hydrogen bonding.

Definition

ChEBI: 1-Ethyl-2-pyrrolidinone is a N-alkylpyrrolidine.

General Description

1-Ethyl-2-pyrrolidone is a transdermal absorption-enhancing compound and mechanism of its effect on multilammellar liposome of stratum corneum lipid has been studied.

Flammability and Explosibility

Non flammable

Side effects

Neurotoxins - Acute Solvent Syndrome
Occupational Hepatotoxin - Secondary Hepatotoxin: Cases of possible toxic effects in an occupational setting depending on human ingestion or experimental poisoning of animals.
Reproductive toxin - A chemical that is toxic to the reproductive system, including offspring defects and damage to male or female reproductive function. Reproductive toxicity includes developmental effects.

Safety Profile

Moderately toxic by ingestion. An eye irritant. Combustible. When heated to decomposition it emits toxic fumes of NOx.

1-Ethyl-2-pyrrolidone(2687-91-4)Related Product Information

• N-Methyl-2-pyrrolidone
• Ethanol
• N-Vinyl-2-pyrrolidone
• Ethyl acrylate
• Ethyl acetate
• N-ethyl-pyrrolidone
• N-Methyl-2-pyrrolidone
• Ethylparaben
• CHLOROETHANE
• Ethylbenzene
• Povidone iodine
• Polyvinylpyrrolidone
• 2-Pyrrolidinone
• Ethyl cellulose
• Diethyl ether
• METHYL-2-PYRROLIDONE
• 1-(3-AMINOPROPYL)-2-PYRROLIDINONE
• 1-Benzyl-2-pyrrolidinone