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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Nucleoside drugs >  Deoxynucleotides and their analogs >  4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

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4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one Basic information

Product Name:
4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonyms:
  • 4-amino-1-[(2r,3r,4r,5r)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 4-AMINO-1-((2R,3R,4R,5R)-3-FLUORO-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDIN-2-ONE
  • 2'-FLUORO-D-CYTIDINE
  • 2'-DEOXY-2'-FLUOROCYTIDINE
  • 2'-FC
  • 2'-FLUORO-2'-DEOXYCYTIDINE
  • 2'-FdC
  • 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)cytosine
CAS:
10212-20-1
MF:
C9H12FN3O4
MW:
245.21
EINECS:
1806241-263-5
Product Categories:
  • Biochemistry
  • Nucleosides and their analogs
  • Nucleosides, Nucleotides & Related Reagents
  • 10212-20-1
  • Nucleosides
  • Modified(deoxy)nucleoside
Mol File:
10212-20-1.mol
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4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one Chemical Properties

Melting point:
167 °C
Boiling point:
500.1±60.0 °C(Predicted)
Density 
1.82±0.1 g/cm3(Predicted)
refractive index 
80 ° (C=1, MeOH)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Soluble in DMSO, Methanol.
pka
12.84±0.70(Predicted)
form 
Powder
color 
White to Off-white
Water Solubility 
Water: 5 mg/mL (20.39 mM; ultrasonic and warming and heat to 60°C)
InChI
InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1
InChIKey
NVZFZMCNALTPBY-XVFCMESISA-N
SMILES
OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](F)[C@@H]1O
CAS DataBase Reference
10212-20-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
HS Code 
29389090
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4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one Usage And Synthesis

Chemical Properties

White Solid

Uses

2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine has been shown to inhibit Borna Disease virus replication and s pread.

Uses

2'-Fluoro-2'-deoxycytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Fluoro-2'-deoxycytidine has been shown to inhibit Borna Disease virus replication and spread.

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-oneSupplier

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