BIG ENDOTHELIN-1 (1-39) (RAT)
BIG ENDOTHELIN-1 (1-39) (RAT) Basic information
- Product Name:
- BIG ENDOTHELIN-1 (1-39) (RAT)
- Synonyms:
-
- CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER: CSCSSLMDKECVYFCHLDIIWVNTPERVVPYGLGSPSRSDISULFIDE BRIDGES CYS1-CYS15, CYS3-CYS11
- H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER-OH
- CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-ARG-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER
- BIG ENDOTHELIN-1 (1-39) (RAT)
- BIG ENDOTHELIN-1 (RAT, 1-39)
- BIG ENDOTHELIN 39 RAT
- BIG ET-1 (1-39) (RAT)
- CAS:
- 135842-15-8
- MF:
- C192H292N50O58S5
- MW:
- 4389
- Product Categories:
-
- Endothelins
- Peptides for Cell Biology
- Precursors
- Mol File:
- Mol File
BIG ENDOTHELIN-1 (1-39) (RAT) Chemical Properties
- storage temp.
- −20°C
- form
- Solid
BIG ENDOTHELIN-1 (1-39) (RAT) Usage And Synthesis
Description
Big endothelin-1(1-39) (RAT) is a 39 amino acid peptide, which is synthesized and secreted by vascular smooth muscle and endothelium cells. It is produced as an inactive enzyme, and is cleaved and activated by serine and aspartic proteases and metalloproteinases. Activated form is called ET-1, which is a potent vasoconstrictor. ET-1 is also produced by the action of endothelin converting enzyme (ECE) on big-ET-1. In guinea pigs, big-ET-1 causes the release of prostanoids and thromboxanes.
Uses
Big endothelin-1(1-39) (RAT) has been used for charting of a standard curve in the study of the role of ET-1 in ventricular dilatation.
Biological Activity
Precursor of Endothelin-1; vasoconstrictor activity appears to be due to its conversion to endothelin 1 by endothelin converting enzyme in the tissue.
BIG ENDOTHELIN-1 (1-39) (RAT)Supplier
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- 21-61263452 13641803416
- ymbetter@glbiochem.com
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- 0510-85629785 18013409632
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- 17705183659
- sales@njleonbiotech.com
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- 025-58361106-805 13082558573
- liugang@njpeptide.com
- Tel
- 0571-87213919
- eric@peptidego.com
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