Coumarin 343 Chemical Properties

Melting point:

240 °C(lit.)

Boiling point:

574.8±50.0 °C(Predicted)

Density 

1.47±0.1 g/cm3(Predicted)

storage temp. 

room temp

solubility 

Chloroform: Slightly soluble: 0.1-1 mg/ml
DMSO: Slightly soluble: 0.1-1 mg/ml

form 

Crystalline Powder

pka

-98.22±0.20(Predicted)

color 

Orange

λmax

443 nm

ε(extinction coefficient)

≥26000 at 441-445nm in ethanol at 0.01g/L

InChI

InChI=1S/C16H15NO4/c18-15(19)12-8-10-7-9-3-1-5-17-6-2-4-11(13(9)17)14(10)21-16(12)20/h7-8H,1-6H2,(H,18,19)

InChIKey

KCDCNGXPPGQERR-UHFFFAOYSA-N

SMILES

C12=C3OC(=O)C(C(O)=O)=CC3=CC3=C1N(CCC3)CCC2

EPA Substance Registry System

1H,5H,11H-[1]Benzopyrano[6,7,8-ij]quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo- (55804-65-4)

Safety Information

Hazard Codes 

Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

37/39-26-24/25

WGK Germany 

3

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Coumarin 343 Usage And Synthesis

Description

Coumarin 519 is a synthetic fluorescent dye widely used in biomedical research. It serves as a valuable tool for studying drug distribution and pharmacokinetics, as well as for monitoring membrane potential and calcium signaling in live cells. Additionally, it finds applications in fluorescence microscopy, flow cytometry, and bioimaging techniques.

Chemical Properties

orange crystalline powder

Uses

Suitable as a laser dye.

Definition

ChEBI: Coumarin 343 is a member of 7-aminocoumarins. It has a role as a fluorochrome.

References

[1] G.A. REYNOLDS  K. H D. New coumarin dyes with rigidized structure for flashlamp-pumped dye lasers[J]. Optics Communications, 1975, 13 3: Pages 222-225. DOI: 10.1016/0030-4018(75)90085-1

Coumarin 343(55804-65-4)Related Product Information

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