METHYL 4-CHLOROBENZOATE Chemical Properties

Melting point:

42-44 °C (lit.)

Boiling point:

136-137°C 10mm

Density 

1,382 g/cm³

refractive index 

1.5800 (estimate)

Flash point:

224 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

color 

Off-White

Merck 

14,2125

BRN 

1564310

LogP

2.870

CAS DataBase Reference

1126-46-1(CAS DataBase Reference)

EPA Substance Registry System

Benzoic acid, 4-chloro-, methyl ester (1126-46-1)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

24/25

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

METHYL 4-CHLOROBENZOATE Usage And Synthesis

Chemical Properties

COLOURLESS TO WHITE CRYSTALS

Uses

Methyl 4-chlorobenzoate was used in quantitative determination of chlorophenoxyisobutyrate (CPIB) and salicylic acid, the metabolites of clofibrate and aspirin, by GC-MS method.

Synthesis Reference(s)

Synthesis, p. 790, 1981 DOI: 10.1055/s-1981-29595

General Description

Methyl 4-chlorobenzoate undergoes room temperature Pd-mediated hydrodehalogenation with KF and polymethylhydrosiloxane (PMHS) to yield methyl benzoate. It undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid in the presence of bis-carbene palladium complex catalyst to yield methyl-(4-phenyl)-benzoate.

METHYL 4-CHLOROBENZOATE(1126-46-1)Related Product Information

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• METHYL 4-CHLOROCINNAMATE
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• METHYL 4-CHLOROBENZOATE
• METHYL 4-CHLORO-2-NITROBENZOATE
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• 4-Chloro-1,8-naphthalic anhydride
• DI-N-BUTYL TETRACHLOROPHTHALATE
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• METHYL 2-CHLOROBENZOATE,METHYL O-CHLOROBENZOATE,METHYL 2-CHLOROBENZOATE, 98+%,Methyl 2-chlorobenzoate 99+%
• METHYL 3-CHLOROBENZOATE,METHYL M-CHLOROBENZOATE
• Methyl4-Methyl-3-Chlorobenzoate