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1-CHLORO-4-IODOBUTANE

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1-CHLORO-4-IODOBUTANE Basic information

Product Name:
1-CHLORO-4-IODOBUTANE
Synonyms:
  • 1-chloro-4-iodo-butan
  • Butane, 1-chloro-4-iodo-
  • TETRAMETHYLENE CHLOROIODIDE
  • 1-CHLORO-4-IODOBUTANE
  • 1-IODO-4-CHLOROBUTANE
  • 4-Chlorobutyl iodide
  • 1-Chloro-4-iodobutane (stabilized with Copper chip)
  • 4-Iodobutyl chloride, 4-Chlorobutyl iodide
CAS:
10297-05-9
MF:
C4H8ClI
MW:
218.46
EINECS:
233-669-4
Product Categories:
  • Organic Building Blocks
  • Alkyl
  • Halogenated Hydrocarbons
Mol File:
10297-05-9.mol
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1-CHLORO-4-IODOBUTANE Chemical Properties

Melting point:
93 °C
Boiling point:
88-89 °C/19 mmHg (lit.)
Density 
1.785 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.54(lit.)
Flash point:
200 °F
storage temp. 
2-8°C(protect from light)
solubility 
Chloroform, Ethyl Acetate
form 
Oil
color 
Clear Colourless
Specific Gravity
1.785
Sensitive 
Light Sensitive
BRN 
1361365
CAS DataBase Reference
10297-05-9(CAS DataBase Reference)
EPA Substance Registry System
Butane, 1-chloro-4-iodo- (10297-05-9)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
TSCA 
Yes
HS Code 
29031980

MSDS

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1-CHLORO-4-IODOBUTANE Usage And Synthesis

Chemical Properties

clear yellow to brown liquid

Uses

1-Chloro-4-iodobutane acts as a reagent in the synthesis of alkyl chromones/quinolones via cyclization/alkylation of enaminones and as an intermediate in many pharmaceutical synthesis.

Uses

1-Chloro-4-iodobutane may be used in the following studies:

  • Preparation of 6-hendecenoic acid.
  • Catalytic asymmetric synthesis of levobupivacaine.
  • Synthesis of alkaloids such as deoxyvasicinone, mackinazolinone.

Definition

ChEBI: 1-Chloro-4-iodobutane is an organoiodine compound.

General Description

1-Chloro-4-iodobutane is a halogenated hydrocarbon. It is an α,ω-dihaloalkane and undergoes electrogenerated Nickel(I) salen (N,N′-bis(salicylidene)ethylenediamine) catalyzed reduction to afford 1,8-dichlorooctane. Electrochemical reduction of 1-chloro-4-iodobutane at glassy carbon cathode has been investigated by cyclic voltammetry and controlled-potential electrolysis.

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