N2,2'-O-DIBUTYRYLGUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
N2,2'-O-DIBUTYRYLGUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Basic information
- Product Name:
- N2,2'-O-DIBUTYRYLGUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
- Synonyms:
-
- MGBPJXVWDGGLKI-GBIKJYCISA-M
- dibutyryl cyclic 3',5'-guanosine monophosphate, sodium
- N2,2μ-O-Dibutyrylguanosine 3μ,5μ-cyclic monophosphate hydrate sodium salt
- Guanosine 3,5-cyclic Monophosphate, N2,2-O-Dibutyryl-, Sodium Salt - CAS 51116-00-8 - Calbiochem
- N2,2μ-O-Dibutyrylguanosine 3μ,5μ-cyclic monophosphate dihydrate sodium salt
- N,2'-O-Dibutyrylguanosine 3',5'-phosphoric acid
- N2,2'-O-Dibutyryl cGMP
- Dibutyryl-Cyclic GMP (sodium salt)
- CAS:
- 51116-00-8
- MF:
- C18H23N5NaO9P
- MW:
- 507.37
- EINECS:
- 2569922
- Product Categories:
-
- Biochemicals and Reagents
- Nucleosides, Nucleotides, Oligonucleotides
- Nucleotide Analogs
- Cyclic Nucleotide Metabolism
- Cyclic Nucleotides and AnalogsSerine/Threonine Kinase Biology
- G Proteins and Cyclic Nucleotides
- Protein Kinase G (PKG)
- Serine/Threonine Kinase Activators
- Mol File:
- 51116-00-8.mol
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N2,2'-O-DIBUTYRYLGUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties
- storage temp.
- −20°C
- solubility
- H2O: 50 mg/mL
- form
- powder
- color
- off-white
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Safety Information
- WGK Germany
- 3
- F
- 10-21
MSDS
- Language:English Provider:SigmaAldrich
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N2,2'-O-DIBUTYRYLGUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Usage And Synthesis
Description
Dibutyryl-cyclic GMP (dibutyryl-cGMP) is a cell-permeable, cGMP analog that activates cGMP-
Uses
Dibutyryl-cGMP is a membrane permeable cGMP analog.
in vivo
Dibutyryl-cGMP (50-200?μg/paw; subcutaneous injection; male Wistar rats) treatment antagonizes the hyperalgesic effect of PGE2 in a dose-dependent manner. Maximal antinociceptive effect of DbcGMP is at 1?h after administration and last for plus 2?h[3].
| Animal Model: | Male Wistar rats (180-?250?g) injection with Prostaglandin E2 (PGE2)[3] |
| Dosage: | 50 μg/paw, 75 μg/paw, 100 μg/paw and 200?μg/paw |
| Administration: | Subcutaneous injection |
| Result: | Antagonized the hyperalgesic effect of PGE2 (2?μg/paw), in a dose-dependent manner. |
N2,2'-O-DIBUTYRYLGUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALTSupplier
Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel
- 400-6206333 13167063860
- anhua.mao@aladdin-e.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
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