4-Bromo-2-methylphenol Chemical Properties

Melting point:

63-67 °C

Boiling point:

63-67°C

Density 

1.3839 (rough estimate)

refractive index 

1.5772 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to lump

pka

9.74±0.18(Predicted)

color 

White to Light yellow to Light orange

Water Solubility 

Slightly soluble in water.

InChI

InChI=1S/C7H7BrO/c1-5-4-6(8)2-3-7(5)9/h2-4,9H,1H3

InChIKey

IWJGMJHAIUBWKT-UHFFFAOYSA-N

SMILES

C1(O)=CC=C(Br)C=C1C

CAS DataBase Reference

2362-12-1(CAS DataBase Reference)

NIST Chemistry Reference

4-Bromo-2-methylphenol(2362-12-1)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-22

Safety Statements 

26-36/37/39-24/25

WGK Germany 

WGK 3

RTECS 

GO6868000

Hazard Note 

Irritant

HazardClass 

IRRITANT, IRRITANT-HARMFUL

HS Code 

29089990

Storage Class

13 - Non Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

4-Bromo-2-methylphenol Usage And Synthesis

Chemical Properties

White solid

Uses

4-Bromo-2-methylphenol, is used as a pharmaceutical intermediate.

Synthesis

o-Toluene ( 1 mmol) was dissolved in 3 mL of ethanol and 1.02 was added to the resulting mixture. mmol of N-bromosuccinimide purified by recrystallization. The resulting mixture was stirred at room temperature for 1 The progress of the reaction was monitored by passing a TLC spot plate to ensure that all the ingredients were fully reacted, and then the solvent ethanol was removed under reduced pressure. Then 10 mL of ethyl acetate and 10 m were added to the reaction system. L distilled water, the mixture was transferred to a partition funnel to separate the organic ( ethyl acetate ) fraction, and then ethyl acetate ( 2 ?? 7 m ) was used to extract the water. L) to extract the aqueous layer. All the ethyl acetate extracts were combined and dried over anhydrous Mg SO4, the organic solvent was spun dry, and the crude product was purified by column chromatographic separation to give the target product molecule 4-bromo-2-methylphenol.

4-Bromo-2-methylphenol(2362-12-1)Related Product Information

• 3-Bromophenol
• 4-Bromo-2-nitrophenol
• Cresol
• 4-Trifluoromethylphenol
• o-Cresol
• Xylenol
• 4-Bromo-2-methylbenzoic acid
• 3-Ethylphenol
• 2-Bromophenol
• m-Cresol
• 2,6-Dimethylphenol
• 4-Bromophenol
• p-Cresol
• 4-BROMO-2-METHYLANILINE
• 4-Bromo-2-hydroxybenzoic acid
• 4-BROMO-2-METHOXYBENZALDEHYDE
• 4,4’-(3h-2,1-benzoxathiol-3-ylidene)bis(2-bromo-6-methylphenol)s,s-dioxid
• Bromine