Nucleoside phosphorylase Chemical Properties

storage temp. 

-20°C

form 

lyophilized powder

color 

White to off-white

InChI

InChI=1/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/s3

InChIKey

MRWXACSTFXYYMV-DOGWMMLDNA-N

SMILES

O1[C@@H](N2C3=C(N=C2)C=NC=N3)[C@H](O)[C@H](O)[C@H]1CO |&1:1,11,13,15,r|

Safety Information

Hazard Codes 

B

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

35079090

MSDS

• Language:English Provider:SigmaAldrich

Nucleoside phosphorylase Usage And Synthesis

Chemical Properties

Powder

Uses

Nucleoside Phosphorylase from microorganisms has been used:

• in phosphopentomutase assay for adenosine synthesis
• for the conversion of 7-methylthioguanosine to 7-methylthioguanine
• in the synthesis of cytokinins in lyophilized cotton plant samples

General Description

Nucleoside Phosphorylase are trimeric and have a molecular mass of about 100 kDa. Each monomer consists of a mixed β-sheet core flanked by eight α-helices and a purine binding in hydrophobic pocket.

Biochem/physiol Actions

Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine. Mutations in the PNP gene are responsible for purine nucleoside phosphorylase deficiency.

Nucleoside phosphorylase(9030-21-1)Related Product Information

• Recombinant Ribokinase from E. coli
• Recombinant Ketol-acid reductoisomerase from Mycobacterium tuberculosis
• Recombinant Adenosine deaminase from Pseudomonas aeruginosa
• Hyaluronidase
• Recombinant Herpes simplex virus (HSV-1) thymidine kinase
• Recombinant Ribosomal-protein-serine acetyltransferase from E. coli
• Recombinant Adenine phosphoribosyltransferase from E. coli
• Recombinant Ribose-phosphate pyrophosphokinase from E. coli
• TERT-BUTYL ISOCYANIDE
• COBALT(II) ACETYLACETONATE
• DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
• Tris(2,4-pentanedionato)chroMiuM(III)
• PHENYLSELENOL
• Cupric acetylacetonate
• Benzyl isocyanide
• 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
• Aluminum acetylacetonate
• GLCNAC1-B-PNP