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Diethyl methylphosphonate

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Diethyl methylphosphonate Basic information

Product Name:
Diethyl methylphosphonate
Synonyms:
  • DEMP
  • Diethoxymethylphosphine oxide
  • diethylmethanephosphate
  • methyl-phosphonicacidiethylester
  • o,o-Diethyl methylphosphonate
  • Phosphonic acid, methyl-, diethyl ester
  • Phosphonicacid,methyl-,diethylester
  • METHYLPHOSPHONIC ACID DIETHYL ESTER
CAS:
683-08-9
MF:
C5H13O3P
MW:
152.13
EINECS:
211-667-4
Product Categories:
  • C-C Bond Formation
  • Horner-Wadsworth-Emmons Reagents
  • Olefination
Mol File:
683-08-9.mol
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Diethyl methylphosphonate Chemical Properties

Boiling point:
194 °C(lit.)
Density 
1.041 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.414(lit.)
Flash point:
168 °F
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
color 
Clear colorless to pale yellow
Water Solubility 
Miscible with water.
BRN 
1753416
Stability:
Hygroscopic
CAS DataBase Reference
683-08-9(CAS DataBase Reference)
NIST Chemistry Reference
Diethyl methanephosphonate(683-08-9)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
SZ9085000
HS Code 
29310095

MSDS

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Diethyl methylphosphonate Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

Diethyl methylphosphonate is used as a precursor for the synthesis of gem-difluroalkenyphosphonate via reaction with alpha-trifluromethylstyrene. It is also used in the synthesis of phosphonylated peptides, fluoroalkyl alpha- and beta-aminophosphonates, pyridone alkaloids with neuritogenic activity and lipophilic meropenem-derived prodrugs. It is readily mineralized by photoexcited titanium dioxide (TiO2).

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