Methyl 2-chloroacetoacetate Chemical Properties

Melting point:

-33--32.7 °C (lit.)

Boiling point:

137 °C (lit.)

Density 

1.236 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.446(lit.)

Flash point:

161 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

Liquid

pka

7.89±0.46(Predicted)

color 

Clear yellow

Water Solubility 

50 g/L (20 ºC)

CAS DataBase Reference

4755-81-1(CAS DataBase Reference)

NIST Chemistry Reference

Butanoic acid, 2-chloro-3-oxo-, methyl ester(4755-81-1)

EPA Substance Registry System

Methyl 2-chloroacetoacetate (4755-81-1)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38-22

Safety Statements 

26-27-28-36/37/39-37/39

RIDADR 

UN 2810 6.1/PG 3

WGK Germany 

3

HazardClass 

8

PackingGroup 

III

HS Code 

29183000

MSDS

• Language:English Provider:Methyl 2-chloroacetoacetate
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

Methyl 2-chloroacetoacetate Usage And Synthesis

Chemical Properties

CLEAR YELLOW LIQUID

Uses

Methyl 2-chloroacetoacetate was used in one-pot synthesis of 2-arylimidazole-4-carboxylic acids. It was also used in synthesis of 3,5-disubstituted 1,2,4-triazoles.

Synthesis Reference(s)

Synthesis, p. 188, 1987 DOI: 10.1055/s-1987-27886

Methyl 2-chloroacetoacetate(4755-81-1)Related Product Information

• Ethyl 2-chloroacetoacetate
• ACETYLSALICYLIC ACID METHYL ESTER
• Methyl acetate
• Ethyl 4,4,4-trifluoroacetoacetate
• Methyl acetoacetate
• Methyl levulinate
• Methyl acrylate
• Kresoxim-methyl
• Chloromethyl pivalate
• Acetoxyacetic acid
• Ethyl acetoacetate
• Bensulfuron methyl
• Methyl chloroacetate
• tert-Butyl acetoacetate
• Thiophanate-methyl
• Methylparaben
• METHYL THIOPHENE-2-CARBOXYLATE
• Methyl