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Apramycin sulfate

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Apramycin sulfate Basic information

Product Name:
Apramycin sulfate
Synonyms:
  • APRAMYCIN SULPHATE
  • APRAMYCIN SULFATE SALT
  • 5-AMINO-2-[[9-AMINO-8-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXOXY)-5-HYDROXY-4-METHYLAMINO-2,7-DIOXABICYCLO[4.4.0]DEC-3-YL]OXY]-6-(HYDROXYMETHYL)OXANE-3,4-DIOL
  • NEBRAMYCIN II SULFATE
  • ApraMycin sulf
  • Apramycin sulfate solution,1000ppm
  • D-Streptamine, O-4-amino-4-deoxy-α-D-glucopyranosyl-(1→8)-O-(8R)-2-amino-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranosyl-(1→4)-2-deoxy-, sulfate (1:)
  • Apramycin sulfate Solution Solution, 100ppm
CAS:
65710-07-8
MF:
C21H43N5O15S
MW:
637.66
EINECS:
265-890-7
Product Categories:
  • SOLODYN
  • antibiotic
  • Amines
  • Intermediates & Fine Chemicals
  • Oligosaccharides
  • Pharmaceuticals
  • Active Pharmaceutical Ingredients
  • Peptide Synthesis/Antibiotics
  • Inhibitors
Mol File:
65710-07-8.mol
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Apramycin sulfate Chemical Properties

Melting point:
>168°C (dec.)
Boiling point:
823℃
Density 
1.56
Flash point:
451.6°(845°F)
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: soluble25mg/mL
form 
powder
color 
white to light yellow
Water Solubility 
Soluble in water.
JECFA Number
75
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Safety Information

Hazard Codes 
T,Xn
Risk Statements 
61-35-36/37/38-20/21/22-36/38
Safety Statements 
53-26-36/37/39-45-36
WGK Germany 
3
F 
10
HS Code 
29419000
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Apramycin sulfate Usage And Synthesis

Chemical Properties

Pale Yellow Solid

Uses

antibacterial; LD50(iv) 280mg/kg(mouse)

Uses

Apramycin sulfate binds to the deep groove of RNA and effectively inhibits ribosomal translocation prohibiting protein synthesis.

Uses

Apramycin sulfate is a broad spectrum aminocyclitol antibiotic and component of the Nebramycin complex, produced by a strain of Streptomyces tenebrarius. Antibacterial.

Definition

ChEBI: Apramycin sulfate is a glycoside and an amino cyclitol.

Apramycin sulfateSupplier

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