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DL-ADRENALINE HYDROCHLORIDE

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DL-ADRENALINE HYDROCHLORIDE Basic information

Product Name:
DL-ADRENALINE HYDROCHLORIDE
Synonyms:
  • (±)-4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol hydrochloride
  • Adrenaline Hcl, racepinephrine hcl
  • (±)-Epinephrine hydrochloride,(±)-Adrenalin, 4-(1-Hydroxy-2-[methylamino]ethyl)-1,2-benzenediol hydrochloride
  • Racepinephrine/Adrenaline HCL
  • Adrenalin HCL
  • 1,2-Benzenediol, 4-1-hydroxy-2-(methylamino)ethyl-, hydrochloride
  • rs-epinephrine hcl
  • RACEPINEPHRINEHYDROCHLORIDE,USP
CAS:
329-63-5
MF:
C9H14ClNO3
MW:
219.67
EINECS:
206-346-0
Product Categories:
  • API
  • 329-63-5
Mol File:
329-63-5.mol
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DL-ADRENALINE HYDROCHLORIDE Chemical Properties

Melting point:
157°
storage temp. 
2-8°C
solubility 
H2O: >50 mg/mL
form 
A crystalline solid
Water Solubility 
H2O: 50mg/mL
Merck 
14,3619
Stability:
Stable, but light sensitive. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
InChI
InChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H
InChIKey
ATADHKWKHYVBTJ-UHFFFAOYSA-N
SMILES
C1(C(O)CNC)=CC=C(O)C(O)=C1.Cl
CAS DataBase Reference
329-63-5(CAS DataBase Reference)
EPA Substance Registry System
(+-)-Epinephrine hydrochloride (329-63-5)
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Safety Information

Hazard Codes 
T
Risk Statements 
24/25-36/37/38
Safety Statements 
26-36/37-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
DO3330000
TSCA 
TSCA listed
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
2937901500
Storage Class
3 - Flammable liquids
Hazard Classifications
Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1

MSDS

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DL-ADRENALINE HYDROCHLORIDE Usage And Synthesis

Chemical Properties

solid

Uses

An adrenergic receptor agonist.

Uses

(±)-Epinephrine hydrochloride has been used:

  • in the induction of renalase expression in Human renal proximal tubular epithelial cells
  • in the infusion studies to test its effect on heart rate and eye temperature measurements in bull
  • as a medium supplement for the stimulation of endothelial progenitor cells

Uses

bronchodilatator,

General Description

Epinephrine (adrenalin) is synthesized from norepinephrine (noradrenalin) by the action of the enzyme phenylethanolamine N-methyltransferase. Epinephrine comprises 5%-10% of the total catecholamines in the central nervous system. It is a mixed α/β-adrenergic receptor agonist and stimulates these receptors. Their site of synthesis is adrenal medulla and it travels through the vascular systems. Its breakdown occurs in the central nervous system (CNS), liver and kidney.

Biochem/physiol Actions

Epinephrine improves systemic pressure during cardiopulmonary resuscitation and is used post cardiac arrest. The levels of epinephrine increases during trauma, sepsis and hypoglycemia resulting in increased cardiac rate and contractility. It is used in the treatment of acute anaphylaxis. Use of epinephrine hydrochloride enables dilation of pupil during intraocular lens (IOL) implantation surgery.

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