SUC-TYR-VAL-ALA-ASP-PNA
SUC-TYR-VAL-ALA-ASP-PNA Basic information
- Product Name:
- SUC-TYR-VAL-ALA-ASP-PNA
- Synonyms:
-
- SUC-TYR-VAL-ALA-ASP-PNA
- SUC-YVAD-PNA
- N-(3-Carboxy-1-oxopropyl)-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-alpha-asparagine
- Caspase-1 and Caspase-4 Chromogenic Substrate
- CASPASE-1 AND CASPASE-4 CHROMOGENIC SUBSTRATE;SUC-TYR-VAL-ALA-ASP-P-NITROANILIDE;SUC-YVAD-PNA
- Suc-Tyr-Val-Ala-Asp-p-nitroanilide
- (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-(3-carboxypropanoylamino)-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-(4-nitroanilino)-4-oxobutanoic acid
- L-α-Asparagine, N-(3-carboxy-1-oxopropyl)-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)- (9CI)
- CAS:
- 208264-84-0
- MF:
- C31H38N6O12
- MW:
- 686.67
- Mol File:
- 208264-84-0.mol
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SUC-TYR-VAL-ALA-ASP-PNA Chemical Properties
- Boiling point:
- 1186.9±65.0 °C(Predicted)
- Density
- 1.404±0.06 g/cm3(Predicted)
- storage temp.
- -15°C
- solubility
- Acetic Acid (50%): soluble
- form
- A solid
- pka
- 4.04±0.10(Predicted)
- Sequence
- {Suc}-Tyr-Val-Ala-Asp-pNA
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SUC-TYR-VAL-ALA-ASP-PNA Usage And Synthesis
Uses
Suc-YVAD-pNA is a substrate of ICE. Interleukin-1β-converting enzyme (ICE) is a cysteine protease responsible for the cleavage of pre-interleukin-1β (pre-IL-1β) to the mature cytokine and a member of a family of related proteases (the caspases)[1].
References
[1] N Margolin, et al. Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases. J Biol Chem. 1997 Mar 14;272(11):7223-8. DOI:10.1074/jbc.272.11.7223
SUC-TYR-VAL-ALA-ASP-PNASupplier
GL Biochem (Shanghai) Ltd
- Tel
- 21-61263452 13641803416
- ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
Chemsky（shanghai）International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
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SUC-TYR-VAL-ALA-ASP-PNA(208264-84-0)Related Product Information
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