Sulfamonomethoxine Chemical Properties

Melting point:

203-2060C

Boiling point:

513℃

Density 

1.3936 (rough estimate)

refractive index 

1.6200 (estimate)

Flash point:

>110°(230°F)

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

methanol: soluble10mg/mL

pka

pKa 5.94 (Uncertain)

form 

powder

color 

white to white with yellow cast

Water Solubility 

Soluble in water at 10mg/ml with warming. Also soluble in ethanol or methanol

BRN 

621128

InChI

InChI=1S/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15)

InChIKey

WMPXPUYPYQKQCX-UHFFFAOYSA-N

SMILES

C1(S(NC2C=C(OC)N=CN=2)(=O)=O)=CC=C(N)C=C1

CAS DataBase Reference

1220-83-3(CAS DataBase Reference)

EPA Substance Registry System

Sulfamonomethoxine (1220-83-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-43

Safety Statements 

26-36

WGK Germany 

2

RTECS 

WP0550000

HazardClass 

IRRITANT

HS Code 

29350090

Toxicity

LD50 oral in rabbit: > 10gm/kg

MSDS

• Language:English Provider:SigmaAldrich

Sulfamonomethoxine Usage And Synthesis

Chemical Properties

White To Off-White Crystalline Powder

Uses

antibacterial

Uses

Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim are used for treating porcine unknown hyperpyrexia.

Definition

ChEBI: Sulfamonomethoxine is a sulfonamide and a member of benzenes.

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 2764, 1961 DOI: 10.1021/jo01066a034

General Description

Chemical structure: sulfonamide

Biochem/physiol Actions

Sulfamonomethoxine is a competitive inhibitor of dihydropteroate synthetase used to block the synthesis of folic acid.

Sulfamonomethoxine(1220-83-3)Related Product Information

• Aniline
• Sulfadimethoxine sodium salt
• Sulfameter
• Sulfadiazine
• Sulfadimethoxine
• Sulfanilamide
• Tris(hydroxymethyl)aminomethane
• Sulfanilic acid
• Sulfasalazine
• Vinyltrimethoxysilane
• ALTRENOGEST
• 4-Aminobenzoic acid
• Glycine
• Sulfamethazine
• 6-Aminocaproic acid
• 4-Amino-benzenesulfonic acid monosodium salt
• (Trifluoromethoxy)benzene
• Sulfamonomethoxine sodium