4-Hydroxy-6-methyl-2-pyrone Chemical Properties

Melting point:

188-190 °C (dec.) (lit.)

Boiling point:

174.21°C (rough estimate)

Density 

1.2048 (rough estimate)

refractive index 

1.4189 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

8.6g/l

form 

Powder

pka

5.14±0.30(Predicted)

color 

Off-white to brown

Water Solubility 

8.60 g/L (20 ºC)

BRN 

113815

CAS DataBase Reference

675-10-5(CAS DataBase Reference)

EPA Substance Registry System

2H-Pyran-2-one, 4-hydroxy-6-methyl- (675-10-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

RTECS 

UQ1000000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29322980

MSDS

• Language:English Provider:4-Hydroxy-6-methyl-2-pyrone
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4-Hydroxy-6-methyl-2-pyrone Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

4-Hydroxy-6-methylpyran-2-one was used in the synthesis of pyrano[3,2-c]pyridones with antiproliferative and apoptosis inducing activities. It was also used in the design of benzisothiazolone human leukocyte elastase inhibitors.

Definition

ChEBI: Triacetate lactone is a member of 2-pyranones. It is a conjugate acid of a triacetate lactone oxoanion.

Synthesis Reference(s)

Synthetic Communications, 20, p. 1931, 1990 DOI: 10.1080/00397919008053123

4-Hydroxy-6-methyl-2-pyrone(675-10-5)Related Product Information

• Tetrahydropyran
• Bensulfuron methyl
• Methylparaben
• Hyaluronic acid
• CHLOROPHOSPHONAZO III
• Methanol
• 4'-Hydroxyacetophenone
• Centchroman
• Tetrahydro-4H-pyran-4-one
• Methyl acrylate
• Ethyl 2-(Chlorosulfonyl)acetate
• Folic acid
• METSULFURON METHYL
• TRIOXSALEN
• Methyl cellulose
• Kresoxim-methyl
• Methyl
• Methyl bromide