Dimethyldioctadecylammonium bromide Chemical Properties

Melting point:

~160 °C

Density 

1.047

RTECS 

RG0185984

refractive index 

1.5260 (estimate)

storage temp. 

-20°C

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Hexanes (Slightly, Heated)

form 

Granular Powder

color 

White

BRN 

3580323

Stability:

Stable. Incompatible with strong oxidizing agents.

CAS DataBase Reference

3700-67-2(CAS DataBase Reference)

EPA Substance Registry System

1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, bromide (3700-67-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-43

Safety Statements 

26-37/39

WGK Germany 

3

TSCA 

Yes

HazardClass 

9

HS Code 

29211990

MSDS

• Language:English Provider:DDAB
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Dimethyldioctadecylammonium bromide Usage And Synthesis

Description

18:0 DDAB is a double-chained quaternary ammonium surfactant with a bromide counter ion.

Chemical Properties

white powder

Uses

Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV).

General Description

18:0 DDAB is cationic lipid and a quaternary ammonium salt. The hydrocarbon tails are saturated unlike the ionizable lipids.

Biochem/physiol Actions

18:0 DDAB is a surface-active molecule, used as an adjuvant to induce systemic immune response. It is non-toxic.

Purification Methods

Crystallise the bromide from acetone, then MeOH [Lukac J Am Chem Soc 106 4387 1984]. Also purify it by chromatography on alumina by washing with *C6H6 and eluting with Me2CO, evaporating and crystallising from MeCN [Swain & Kreevoy J Am Chem Soc 77 1126 1955]. [Beilstein 4 IV 829.]

Dimethyldioctadecylammonium bromide(3700-67-2)Related Product Information

• N,N-Dimethylformamide
• Sodium bromate
• Tetraethylammonium bromide
• Clidinium bromide
• Tetrabutylammonium bromide
• Ammonium bromide
• Ethidium bromide
• 1,1,1,3,5,5,5-Heptamethyltrisiloxane
• Dioctadecyl dimethyl ammonium chloride
• Dimercaptodimethylammonium chloride
• Didodecylamine
• Didodecyl dimethyl ammonium chloride
• Didecyl dimethyl ammonium chloride
• Dimethylditetradecylammonium bromide
• Didodecyldimethylammonium bromide
• Dihexadecyldimethylammonium chloride
• Didecyldimethylammonium bromide
• Dihexadecyldimethylammonium bromide