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3-Hydroxypicolinic acid

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3-Hydroxypicolinic acid Basic information

Product Name:
3-Hydroxypicolinic acid
Synonyms:
  • 2-PYRIDINECARBOXYLIC ACID, 3-HYDROXY-
  • 3-HYDROXYPYRIDINE-2-CARBOXYLIC ACID
  • 3-HYDROXYPICOLINIC ACID
  • 3-HPA
  • 3-HYDROXY-2-PYRIDINECARBOXYLIC ACID
  • TIMTEC-BB SBB006727
  • RARECHEM AL BO 0972
  • 3-Hydroxy-2-Pyridinecarboxylic
CAS:
874-24-8
MF:
C6H5NO3
MW:
139.11
EINECS:
212-859-0
Product Categories:
  • alcohol| carboxylic acid
  • Pyridine
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
  • Pyridine series
  • Organic acids
  • Pyridines
  • Analytical Chemistry
  • Mass Spectrometry
  • Matrix Materials (MALDI-TOF-MS)
Mol File:
874-24-8.mol
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3-Hydroxypicolinic acid Chemical Properties

Melting point:
213-218 °C (lit.)
Boiling point:
255.04°C (rough estimate)
Density 
1.4429 (rough estimate)
refractive index 
1.5423 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Acetonitrile (Slightly), DMSO (Slightly)
form 
Fine Powder
pka
1.14±0.50(Predicted)
color 
White to almost white
Water Solubility 
Soluble in water (0.25g in 10ml).
BRN 
118954
CAS DataBase Reference
874-24-8(CAS DataBase Reference)
NIST Chemistry Reference
3-Hydroxypicolinic acid(874-24-8)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/22
Safety Statements 
26-28-36/37/39-36
WGK Germany 
3
10
HazardClass 
IRRITANT
HS Code 
29333990

MSDS

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3-Hydroxypicolinic acid Usage And Synthesis

Chemical Properties

Light yellow Needles

Uses

3-Hydroxypicolinic acid (3-HPA) is a matrix material used in matrix-assisted laser desorption/ionization (MALDI) based mass spectroscopy (MS) for the analysis of large biomolecules and quantification of oligonucleotides.

Definition

ChEBI: A monohydroxypyridine that is picolinic acid in which the hydrogen at position 3 is replaced by a hydroxy group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of oligonucleotides.

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