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Chlorodifluoroacetic acid ethyl ester

Basic information Safety Supplier Related

Chlorodifluoroacetic acid ethyl ester Basic information

Product Name:
Chlorodifluoroacetic acid ethyl ester
Synonyms:
  • Ethyl chlorodifluoroacetate 98%
  • Ethyl 2-chloro-2,2-difluoroacetate
  • Ethyl chlorodifluoroethanoate
  • Difluorochloroacetic acid ethyl ester
  • Ethyl chlorodifluoroacetate, Chlorodifluoroacetic acid ethyl ester
  • Ethyl 2-chloro-2,2-difluoroethanoate, Chloro(difluoro)acetic acid ethyl ester
  • Ethyl chloroacetatetwo fluorine
  • Acetic acid,2-chloro-2,2-difluoro-, ethyl ester
CAS:
383-62-0
MF:
C4H5ClF2O2
MW:
158.53
EINECS:
206-850-0
Product Categories:
  • C2 to C5
  • Carbonyl Compounds
  • Fluorinated Building Blocks
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Synthetic Organic Chemistry
  • Esters
  • Pharmaceutical Intermediates
Mol File:
383-62-0.mol
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Chlorodifluoroacetic acid ethyl ester Chemical Properties

Boiling point:
96-97.5 °C (lit.)
Density 
1.252 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.358(lit.)
Flash point:
65 °F
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Ethyl Acetate (Sparingly)
form 
clear liquid
color 
Colorless to Almost colorless
Specific Gravity
1.252
Sensitive 
Moisture Sensitive
BRN 
1761413
CAS DataBase Reference
383-62-0(CAS DataBase Reference)
EPA Substance Registry System
Acetic acid, chlorodifluoro-, ethyl ester (383-62-0)
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Safety Information

Hazard Codes 
F,C,Xi
Risk Statements 
11-34-20/21/22
Safety Statements 
16-26-27-36/37/39-45
RIDADR 
UN 2924 3/PG 2
WGK Germany 
3
Hazard Note 
Flammable
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29159000

MSDS

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Chlorodifluoroacetic acid ethyl ester Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

Ethyl chlorodifluoroacetate (ECDFA) may be used as a starting reagent in the synthesis of 3-gem-difluoro-2-ethoxy allylic alcohols.

General Description

Ethyl chlorodifluoroacetate (ECDFA) undergoes Reformatskii reaction with various aldehydes in DMF. It reacts with phenylacetylene to afford ethyl α,α?difluoro-4-phenyl-3-butenoates.

Chlorodifluoroacetic acid ethyl ester Preparation Products And Raw materials

Preparation Products

Chlorodifluoroacetic acid ethyl esterSupplier

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