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N-DESMETHYLCITALOPRAM HYDROCHLORIDE

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N-DESMETHYLCITALOPRAM HYDROCHLORIDE Basic information

Product Name:
N-DESMETHYLCITALOPRAM HYDROCHLORIDE
Synonyms:
  • DEMETHYLCITALOPRAM
  • 1-(4-Fluoro-phenyl)-1-(3-methylamino-propyl)-1,3-dihydro-isobenzofuran-5-carbonitril
  • rac Demethyl Citalopram
  • S-Desmethylcitalopram
  • 1-(4-Fluoro-phenyl)-1-(3-methylamino-propyl)-1,3-dihydro-isobenzofuran-5-carbonitrile Hydrochloride
  • Citalopram impurity 4/Citalopram EP Impurity D HCl/(S)-N-Desmethyl Citalopram Hydrochloride
  • racDemethyl Citalopram Hydrochloride
  • 1-(4-Fluoro-phenyl)-1-(3-methylamino-propyl)-1,3-dihydro-isobenzofuran-5-carbonitrile
CAS:
144025-14-9
MF:
C19H19FN2O
MW:
310.37
Product Categories:
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Various Metabolites and Impurities
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
144025-14-9.mol
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N-DESMETHYLCITALOPRAM HYDROCHLORIDE Chemical Properties

Melting point:
60-65°C
Boiling point:
429.4±45.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
pka
10.50±0.10(Predicted)
Stability:
Hygroscopic
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
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N-DESMETHYLCITALOPRAM HYDROCHLORIDE Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

N-Desmethylcitalopram hydrochloride is a metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant.

General Description

N-Desmethylcitalopram is an active metabolite of the SSRI antidepressant drug citalopram. Citalopram, marketed as Celexa? in the US and Canada, is used to treat major depression associated with mood disorders.

N-DESMETHYLCITALOPRAM HYDROCHLORIDESupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
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Artis Chemistry (Shanghai) Co. Ltd.
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