2-Phenylbutyric acid Chemical Properties

Melting point:

39-42 °C (lit.)

Boiling point:

270-272 °C (lit.)

Density 

0,62 g/cm³

refractive index 

1.5150

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Solid

pka

4.34±0.10(Predicted)

color 

White adhering crystalline powder

Water Solubility 

insoluble

BRN 

509876

CAS DataBase Reference

90-27-7(CAS DataBase Reference)

NIST Chemistry Reference

Benzeneacetic acid, «alpha»-ethyl-(90-27-7)

EPA Substance Registry System

Benzeneacetic acid, .alpha.-ethyl- (90-27-7)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-20/21/22

Safety Statements 

22-36

WGK Germany 

3

RTECS 

ET5957500

TSCA 

Yes

HS Code 

29163900

Toxicity

LD50 orl-mus: 1154 mg/kg BCFAAI 100,143,61

MSDS

• Language:English Provider:alpha-Ethylphenylacetic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Phenylbutyric acid Usage And Synthesis

Chemical Properties

white to yellowish adhering crystals with aromatic odor.

Uses

2-Phenylbutyric Acid is a metabolite of Butamirate. It exists in all living organisms, ranging from bacteria to humans. It is used as an antihyperlipidemic drug.

Definition

ChEBI: 2-phenylbutyric acid is a monocarboxylic acid that is butyric acid substituted by a phenyl group at position 2. It has a role as a human xenobiotic metabolite. It is a monocarboxylic acid and a member of benzenes. It derives from a butyric acid.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 31, p. 2564, 1983 DOI: 10.1248/cpb.31.2564

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. A combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes.

2-Phenylbutyric acid(90-27-7)Related Product Information

• 1-Phenyl-2-nitropropene
• 4-Phenylbutyric acid
• 1-PHENYL-2-PROPANOL
• Ethyl 2-(Chlorosulfonyl)acetate
• Glycine
• Folic acid
• Citric acid
• Isobutyric acid
• α-Lipoic Acid
• 4-Aminobutyric acid
• Indole-3-butyric acid
• N,N-Dimethylpropionamide
• 2,2-Dimethylbutyryl chloride
• 2-Phenylbutyryl chloride
• Indobufen Impurity 2
• 4-Nitrophenylacetic acid
• Benzeneacetic acid, α-ethyl-2-nitro-
• Indobufen Impurity 9